Effects of inulin-type fructans consumption on mineral intestinal absorption and balance in rats fed control and iron-deficient diets



Título del documento: Effects of inulin-type fructans consumption on mineral intestinal absorption and balance in rats fed control and iron-deficient diets
Revue: Alimentos e nutricao
Base de datos: PERIÓDICA
Número de sistema: 000340099
ISSN: 0103-4235
Autores: 1
2
3
4
Instituciones: 1Universidade de Sao Paulo, Faculdade de Farmacia, Sao Paulo. Brasil
2Universidade de Sao Paulo, Faculdade de Ciencias Farmaceuticas, Sao Paulo. Brasil
3Universidade de Sao Paulo, Departamento de Alimentos e Nutricao Experimental, Sao Paulo. Brasil
Año:
Periodo: Ene-Mar
Volumen: 21
Número: 1
Paginación: 7-13
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Experimental
Resumen en inglés In this study, the effects of inulin-type fructans (ITF) consumption on mineral absorption (Ca, Mg, Cu, Fe and Zn) and balance (Ca and Mg) were evaluated in rats fed control and iron-defi cient diets. Each of 24 male Wistar rats (4-wk old) was assigned to 1 of 4 groups derived from 2×2 factorial design with 2 levels of added Fe (0 and 35 mg/kg) and ITF (0 and 100 g/kg) for 33 d. The food intake was determined daily and body weight recorded every two days. Food and demineralized water were offered ad libitum. Feces and urine were quantitatively collected for 5 d from day 23 of the test period, pooled, and stored at -20ºC for mineral analysis. ITF consumption increased Ca absorption (P < 0.05) only in non-defi cient rats, whereas Mg absorption was positively affected irrespective of Fe status of the animals. Unexpectedly, Cu absorption was impaired by ITF. Furthermore, Fe defi ciency negatively affected the absorption of Mg and Zn (P < 0.001). In conclusion, ITF consumption positively affected the absorption of Ca and Mg. However, Fe and Zn absorption were unchanged and Cu was negatively affected by ITF supplementation. The effects of ITF consumption on Cu homeostasis is unknown and should be considered in future research
Disciplinas: Química,
Biología,
Medicina
Palabras clave: Bioquímica,
Fisiología animal,
Metabolismo y nutrición,
Fructanos tipo inulina,
Calcio,
Magnesio,
Absorción intestinal,
Ratas
Keyword: Chemistry,
Biology,
Medicine,
Biochemistry,
Animal physiology,
Metabolism and nutrition,
Inulin-type fructans,
Calcium,
Magnesium,
Intestinal absorption
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