Journal: | Visión electrónica |
Database: | PERIÓDICA |
System number: | 000461400 |
ISSN: | 1909-9746 |
Authors: | Fonseca Velásquez, Aldemar1 |
Institutions: | 1Universidad Distrital Francisco José de Caldas, Bogotá. Colombia |
Year: | 2014 |
Season: | Ene-Jun |
Volumen: | 8 |
Number: | 1 |
Pages: | 6-18 |
Country: | Colombia |
Language: | Inglés |
Document type: | Artículo |
Approach: | Experimental aplicado |
English abstract | bone remodeling is the biological process through which old bone tis-sue is transformed into new bone through the action of a basic unit of bone remodeling (bmu). This paper presents a computational model to determine the variation of cell population caused by the presence of micro-fractures within the bmu during the remodeling process, also determines the spatial evolution at particular points of the trabecular bone surface. The remodeling process presented is governed by a two-dimensional cellular automaton that evolves according to a set of rules and states, based on biological processes that occur in bone remodeling. The simulation of the remodeling process, programmed in maTLab® performed in time intervals of 0.3 seconds, in the model showed a ratio of 20 osteoclasts to 190 osteoblasts. On the other hand, an approximate resorption time of 34 days and 150 days for formation was obtained. bone mass showed a maximum percentage loss of 19% |
Disciplines: | Ciencias de la computación, Medicina |
Keyword: | Conteo celular, Estructura trabecular, Modelos computacionales, Remodelación ósea |
Keyword: | Bone remodelling, Cell count, Computational models, Trabecular structure |
Full text: | https://revistas.udistrital.edu.co/index.php/visele/article/view/7855/9586 |