| Revista: | Visión electrónica |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000461400 |
| ISSN: | 1909-9746 |
| Autores: | Fonseca Velásquez, Aldemar1 |
| Instituciones: | 1Universidad Distrital Francisco José de Caldas, Bogotá. Colombia |
| Año: | 2014 |
| Periodo: | Ene-Jun |
| Volumen: | 8 |
| Número: | 1 |
| Paginación: | 6-18 |
| País: | Colombia |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental aplicado |
| Resumen en inglés | bone remodeling is the biological process through which old bone tis-sue is transformed into new bone through the action of a basic unit of bone remodeling (bmu). This paper presents a computational model to determine the variation of cell population caused by the presence of micro-fractures within the bmu during the remodeling process, also determines the spatial evolution at particular points of the trabecular bone surface. The remodeling process presented is governed by a two-dimensional cellular automaton that evolves according to a set of rules and states, based on biological processes that occur in bone remodeling. The simulation of the remodeling process, programmed in maTLab® performed in time intervals of 0.3 seconds, in the model showed a ratio of 20 osteoclasts to 190 osteoblasts. On the other hand, an approximate resorption time of 34 days and 150 days for formation was obtained. bone mass showed a maximum percentage loss of 19% |
| Disciplinas: | Ciencias de la computación, Medicina |
| Palabras clave: | Conteo celular, Estructura trabecular, Modelos computacionales, Remodelación ósea |
| Keyword: | Bone remodelling, Cell count, Computational models, Trabecular structure |
| Texto completo: | https://revistas.udistrital.edu.co/index.php/visele/article/view/7855/9586 |
