| Revista: | Veterinaria México OA |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000439057 |
| ISSN: | 2007-5472 |
| Autores: | Aquino, Itzcoatl1 Gutiérrez Blanco, Eduardo2 Ocampo, Luis1 Gutiérrez, Lilia1 Bernad Bernad, María J3 Sumano, Héctor1 |
| Instituciones: | 1Universidad Nacional Autónoma de México, Facultad de Medicina Veterinaria, Ciudad de México. México 2Universidad Autónoma de Yucatán, Facultad de Medicina Veterinaria y Zootecnia, Mérida, Yucatán. México 3Universidad Nacional Autónoma de México, Facultad de Química, Ciudad de México. México |
| Año: | 2019 |
| Periodo: | Jul-Sep |
| Volumen: | 6 |
| Número: | 3 |
| País: | México |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental, aplicado |
| Resumen en inglés | A novel four-week stable experimental formulation of propofol lacking phospholipids (PMICRO) was assessed as an anesthetic agent in dogs and compared to the customary preparation of propofol that contains phospholipids (PMACRO). Forty healthy mixed-breed dogs were included in this study and randomly assigned (blocking by sex and age), to receive 5 mg/kg of one of these two pharmaceutical propofol preparations, by intravenous injection. Basal and post anesthetic blood biochemical parameters were measured. Also, cardiovascular and respiratory rates were recorded. Onset, duration and recovery from anesthesia, were documented as well. Overall, IV administration of PMICRO induces a short duration anesthesia with rapid recovery in a similar manner to anesthesia achieved with the customary propofol preparation (PMACRO). Because PMICRO lacks phospholipids, it may allow a longer storage time, decreasing the likeliness of accidental administration of contaminated propofol |
| Disciplinas: | Medicina veterinaria y zootecnia |
| Palabras clave: | Medicina veterinaria, Propofol, Fosfolípidos, Anestesia, Perros, Microemulsiones |
| Keyword: | Veterinary medicine, Anesthesia, Dogs, Microemulsions, Phospholipids, Propofol |
| Texto completo: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
