The systemic inflammatory response syndrome related to the release of cytokines following severe envenomation



Document title: The systemic inflammatory response syndrome related to the release of cytokines following severe envenomation
Journal: The journal of venomous animals and toxins
Database: PERIÓDICA
System number: 000298641
ISSN: 0104-7930
Authors: 1

Institutions: 1Ben-Gurion University of the Negev, Faculty of Health Sciences, Beer-Sheva. Israel
Year:
Volumen: 5
Number: 1
Pages: 5-33
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Analítico, descriptivo
English abstract Envenomation by insects, snakes, scorpions, and spiders involves the activation of the inflammatory system with the release and activation of pro-inflammatory cytokines, chemotactic mediators, cellular infiltration, and other vasoactive mediators. Activation of the inflammatory system and its cascade of events play a major role in the pathogenesis of envenomation, its clinical picture, and outcome. Additional clinical and laboratory studies are required to characterize the exact mechanisms by which the inflammatory system affects the pathophysiology, clinical course, and complications following envenomations. A better understanding of the involvement of the inflammatory cascade in different envenoming syndromes may have future therapeutic benefits
Disciplines: Medicina
Keyword: Toxicología,
Inmunología,
Respuesta inflamatoria sistémica,
Citocinas,
Mediadores quimiotácticos,
Mediadores vasoactivos
Keyword: Medicine,
Toxicology,
Immunology,
Systemic inflammatory response,
Cytokines,
Chemotactic mediators,
Vasoactive mediators
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