Psychosis during peginterferon-alpha2a and ribavirin therapy: case report



Título del documento: Psychosis during peginterferon-alpha2a and ribavirin therapy: case report
Revista: The brazilian journal of infectious diseases
Base de datos: PERIÓDICA
Número de sistema: 000290998
ISSN: 1413-8670
Autores: 1
2



3
Instituciones: 1Universidade Federal da Bahia, Departamento de Neuropsiquiatria, Salvador, Bahia. Brasil
2Universidade Federal da Bahia, Gastroenterologia, Salvador, Bahia. Brasil
3Universidade Federal de Sao Paulo, Laboratorio de Neurociencias Clinicas, Sao Paulo. Brasil
Año:
Periodo: Dic
Volumen: 10
Número: 6
Paginación: 406-407
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Caso clínico
Resumen en inglés Pegylated Interferon-alpha, combined with ribavirin, gives high sustained virological response in patients with hepatitis C virus, an important public health problem and one of the most frequent chronic infectious diseases worldwide. Though it has therapeutic benefits, treatment with IFN-alpha may be complicated by various side effects, especially symptoms of major depression and acute mania. Psychosis is a rare side effect, and its management usually includes discontinuation of IFN-alpha. We report a case of psychotic disorder that occurred during therapy with pegylated Interferon-alpha given associated with ribavirin. After good response to psychiatric treatment, it became possible to finish the anti-viral therapy
Disciplinas: Medicina,
Química
Palabras clave: Gastroenterología,
Terapéutica y rehabilitación,
Bioquímica,
Terapia antiviral,
Interferón alfa,
Ribavirina,
Hepatitis C,
Psicosis,
Tratamiento psiquiátrico
Keyword: Medicine,
Chemistry,
Gastroenterology,
Therapeutics and rehabilitation,
Biochemistry,
Antiviral therapy,
Interferon alpha,
Ribavirin,
Hepatitis C,
Psychosis,
Psychiatric treatment
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