| Journal: | The brazilian journal of infectious diseases |
| Database: | PERIÓDICA |
| System number: | 000290844 |
| ISSN: | 1413-8670 |
| Authors: | Queiroz, Conceicao1 Travassos, Ana Gabriela Pinheiro, Carla Cristiane Studart, Eduardo2 Araujo-Filho, Jose Bouzas3 Sarno, Carla Kruchewsky4 |
| Institutions: | 1Universidade Federal da Bahia, Departamento de Ginecologia, Salvador, Bahia. Brasil 2Universidade Federal da Bahia, Departamento de Patologia, Salvador, Bahia. Brasil 3Universidade Federal da Bahia, Departamento de Estadistica, Salvador, Bahia. Brasil 4CICAN, Centro Estadual de Oncologia, Salvador, Bahia. Brasil |
| Year: | 2004 |
| Season: | Oct |
| Volumen: | 8 |
| Number: | 5 |
| Pages: | 356-362 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Caso clínico |
| English abstract | Human Papilloma Virus (HPV) plays a central role in the development of cervical cancer. However, other coexisting factors, such as HIV infection, must be present for this to occur. We evaluated the prevalence of HPV in HIV-positive and HIV-negative patients in the city of Salvador , Bahia, Brazil, and determined the most prevalent types of HPV in these patients. Fifty-five cases were selected from among patients attending three institutions providing cervical pathology services in the city of Salvador. HIV testing (Elisa/WB), HPV-DNA testing by PCR, colposcopy, cytology and biopsy were carried out in all patients. The histopathological results were classified as follows: 11 cases were normal/negative for neoplasia, 15 were diagnosed as cervical intraepithelial neoplasia grade 1 (CIN 1), 10 were CIN 2, 15 cases were CIN 3 and there were four cases of invasive squamous cell carcinoma. Among the 55 patients studied, 43 tested positive for HPV-DNA and 20 for HIV. All HIV-positive patients were positive for HPV-DNA. The most prevalent types of HPV were HPV 16, 52, 58, 53, 54, 33 and 51, and there was little difference between the groups of HIV-positive and HIV-negative patients with respect to the type of HPV encountered. The HIV-positive patients were found to be infected with a greater number of types of HPV than the HIV-negative patients. This study corroborates the existence of regional variations in the distribution of certain types of HPV, which is probably due to the particular ethnic constitution found in this region of Brazil |
| Disciplines: | Biología, Medicina |
| Keyword: | Inmunología, Virus, Oncología, Virus del papiloma humano, VIH, Neoplasia intraepitelial cervical, Carcinoma invasivo cervical |
| Keyword: | Biology, Medicine, Immunology, Virus, Oncology, Human papillomavirus (HPV), Human immunodeficiency virus (HIV), Cervical intraepithelial neoplasm, Cervical invasive carcinoma |
| Full text: | Texto completo (Ver HTML) |
