Leptospirosis as a cause of acute respiratory failure: clinical features and outcome in 35 critical care patients



Document title: Leptospirosis as a cause of acute respiratory failure: clinical features and outcome in 35 critical care patients
Journal: The brazilian journal of infectious diseases
Database: PERIÓDICA
System number: 000290697
ISSN: 1413-8670
Authors: 1
Institutions: 1Hospital de Clinicas de Porto Alegre, Unidade de Cuidados Intensivos, Porto Alegre, Rio Grande do Sul. Brasil
Year:
Season: Jun
Volumen: 6
Number: 3
Pages: 135-139
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Caso clínico, analítico
English abstract Leptospirosis may have important complications, such as acute respiratory failure (ARF) associated or not with other organic dysfunction, with a high mortality rate. We report the characteristics and evolution of severe leptospirosis associated with ARF. During 10 years, 35 consecutive adult patients admitted in two general Intensive Care Units with severe leptospirosis and ARF, were followed up. Clinical characteristics, associated organic dysfunction and mortality were analyzed. Survivors were compared with non-survivors. The most frequent clinical manifestations were dyspnea, fever, myalgia, jaundice, hemoptysis and coughing. All patients presented ARF, needing mechanical ventilation, as well as other organic dysfunctions. The mortality rate was 51%. Non-survivors were older and had a higher incidence of organic dysfunction, mainly renal, cardiovascular and neurological failures, as well as a higher level of acidosis. In conclusion, leptospirosis should be considered as a cause of severe ARF and other associated organic dysfunctions
Disciplines: Medicina
Keyword: Microbiología,
Neumología,
Leptospirosis,
Insuficiencia respiratoria aguda
Keyword: Medicine,
Microbiology,
Pneumology,
Leptospirosis,
Acute respiratory failure
Full text: Texto completo (Ver HTML)