Leptospirosis as a cause of acute respiratory failure: clinical features and outcome in 35 critical care patients



Título del documento: Leptospirosis as a cause of acute respiratory failure: clinical features and outcome in 35 critical care patients
Revista: The brazilian journal of infectious diseases
Base de datos: PERIÓDICA
Número de sistema: 000290697
ISSN: 1413-8670
Autores: 1
Instituciones: 1Hospital de Clinicas de Porto Alegre, Unidade de Cuidados Intensivos, Porto Alegre, Rio Grande do Sul. Brasil
Año:
Periodo: Jun
Volumen: 6
Número: 3
Paginación: 135-139
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Caso clínico, analítico
Resumen en inglés Leptospirosis may have important complications, such as acute respiratory failure (ARF) associated or not with other organic dysfunction, with a high mortality rate. We report the characteristics and evolution of severe leptospirosis associated with ARF. During 10 years, 35 consecutive adult patients admitted in two general Intensive Care Units with severe leptospirosis and ARF, were followed up. Clinical characteristics, associated organic dysfunction and mortality were analyzed. Survivors were compared with non-survivors. The most frequent clinical manifestations were dyspnea, fever, myalgia, jaundice, hemoptysis and coughing. All patients presented ARF, needing mechanical ventilation, as well as other organic dysfunctions. The mortality rate was 51%. Non-survivors were older and had a higher incidence of organic dysfunction, mainly renal, cardiovascular and neurological failures, as well as a higher level of acidosis. In conclusion, leptospirosis should be considered as a cause of severe ARF and other associated organic dysfunctions
Disciplinas: Medicina
Palabras clave: Microbiología,
Neumología,
Leptospirosis,
Insuficiencia respiratoria aguda
Keyword: Medicine,
Microbiology,
Pneumology,
Leptospirosis,
Acute respiratory failure
Texto completo: Texto completo (Ver HTML)