| Journal: | The brazilian journal of infectious diseases |
| Database: | PERIÓDICA |
| System number: | 000290842 |
| ISSN: | 1413-8670 |
| Authors: | D'Azevedo, Pedro Alves1 Musskopf, Maiara I Ramos, Carina G Dias, Cicero A.G Goncalves, Ana Lucia S2 |
| Institutions: | 1Fundacao Faculdade Federal de Ciencias Medicas de Porto Alegre, Porto Alegre, Rio Grande do Sul. Brasil 2Irmandade Santa Casa de Misericordia de Porto Alegre, Laboratorio Central de Analises Clinicas, Porto Alegre, Rio Grande do Sul. Brasil |
| Year: | 2004 |
| Season: | Oct |
| Volumen: | 8 |
| Number: | 5 |
| Pages: | 372-377 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Caso clínico |
| English abstract | Extended spectrum beta-lactamase (ESBL) production by Klebsiella sp. and E. coli is an emerging problem. In this study, 107 clinical isolates (53 E. coli, 47 K. pneumoniae and 7 K. oxytoca) screened as ESBL producers by the NCCLS disk diffusion procedure were submitted to a double disk confirmatory test (DDT) and to the E-test double strip for confirmation of ESBL production by demonstration of clavulanic acid inhibition effect (CAIE). Only 72/107 (67%) of the isolates were confirmed as ESBL producers by DDT, with diverse results among species. By the E-test, 58/107 (54%) isolates were confirmed as ESBL producers, and 18/107 (17%) were not determinable. Susceptibility to cefoxitin was found in 57/68 (83%) of strains that did not show CAIE. ESBL detection remains a controversial issue and clinical laboratories are in need of a simple and effective way to recognize strains with this kind of resistance |
| Disciplines: | Biología, Química, Medicina |
| Keyword: | Bacterias, Bioquímica, Farmacología, ESBL, Cefoxitina, Pruebas de sensibilidad, Prueba de detección |
| Keyword: | Biology, Chemistry, Medicine, Bacteria, Biochemistry, Pharmacology, ESBL, Cefoxitin, Susceptibility tests, Screening test |
| Full text: | Texto completo (Ver HTML) |
