Infection with the Mycobacterium avium complex in patients without predisposing conditons: a case report and literature review



Document title: Infection with the Mycobacterium avium complex in patients without predisposing conditons: a case report and literature review
Journal: The brazilian journal of infectious diseases
Database: PERIÓDICA
System number: 000290948
ISSN: 1413-8670
Authors: 1
2
Institutions: 1Hospital Universitario Prof. Edgar Santos, Salvador, Bahia. Brasil
2Fundacao Bahiana para o Desenvolvimento das Ciencias, Escola Bahiana de Medicina e Saude Publica, Salvador, Bahia. Brasil
Year:
Season: Abr
Volumen: 9
Number: 2
Pages: 173-179
Country: Brasil
Language: Inglés
Document type: Reporte técnico
Approach: Caso clínico
English abstract Nontuberculous Mycobacteria (NTM), especially Mycobacterium avium-intracellulare complex (MAC), has been considered responsible for human disease, especially in HIV patients. Nevertheless, it has been diagnosed in immunocompetent elderly men, frequently with previous pulmonary disease: chronic obstructive lung disease (COPD), complications of tuberculosis, pulmonary fibrosis and bronchiectasis. We relate the case of a female patient, 51 years old, with continuously acid fast bacilli (AFB) smears and with three previous treatments, which were conducted at the multiresistant tuberculosis (MRTB) service. MAC was identified in the sputum culture, and she received treatment for one year. The posterior sputum exams were negative. The cavity lesions observed in the high-resolution computed tomography (HRCT) were reduced, and some of the nodule lesions became bronchiectasis, even after the end of treatment. We agree with the literature reports that indicate that MAC is the cause of bronchiectasis. It is necessary to identify the type of mycobacteria in immunocompetent individuals with positive AFB smears that do not become negative with tuberculosis treatment
Disciplines: Medicina
Keyword: Microbiología,
Neumología,
Inmunología,
Mycobacterium avium complex,
Enfermedades pulmonares,
Bronquiectasia,
Inmunocompetencia
Keyword: Medicine,
Microbiology,
Pneumology,
Mycobacterium avium complex,
Pulmonary diseases,
Bronchiectasis,
Immunocompetence,
Immunology
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