| Journal: | The brazilian journal of infectious diseases |
| Database: | PERIÓDICA |
| System number: | 000290648 |
| ISSN: | 1413-8670 |
| Authors: | Mendes, Caio M.F1 Sinto, Sumiko I Oplustil, Carmen Paz |
| Institutions: | 1Fleury Medicina e Saude, Sao Paulo. Brasil |
| Year: | 2001 |
| Season: | Oct |
| Volumen: | 5 |
| Number: | 5 |
| Pages: | 269-276 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Experimental |
| English abstract | This study was conducted to evaluate the activity of azithromycin in comparison to 12 other antibacterial agents against recent isolates obtained consecutively from patients with respiratory tract or skin infections, from January to July, 2000. A total of 717 Gram-positive cocci were analyzed in this study and the following species were studied: Staphylococcus aureus (n=576), beta-hemolytic streptococci ( n=115), and Streptococcus pneumoniae (n=26). Susceptibility testing was carried out by the disk diffusion method and interpreted according to NCCLS breakpoints. The activity of azithromycin was compared to erythromycin, clindamycin, chloramphenicol, ciprofloxacin, ofloxacin, oxacillin, penicillin, ceftriaxone, tetracycline, trimethoprim/sulfamethoxazole, teicoplanin, and vancomycin. Of the 26 S. pneumoniae isolates recovered from the respiratory tract, 5 (19.2%) were intermediate resistant to penicillin. All of these strains were susceptible to chloramphenicol, ofloxacin, and vancomycin, and 24 (92%) were also susceptible to azithromycin, clindamycin, and erythromycin. Among the 67 beta-hemolytic streptococci strains isolated from the respiratory tract, 66 (99%) were susceptible to azithromycin, erythromycin, clindamycin, and ofloxacin. All 48 beta-hemolytic streptococci strains isolated from skin were susceptible to azithromycin and clindamycin, 47 (98%) were susceptible to erythromycin, and 46 (96%) were susceptible to ofloxacin. Of the 576 strains of S. aureus, 253 (43.9%) were isolated from the respiratory tract and 323 (56.1% |
| Disciplines: | Biología, Medicina |
| Keyword: | Bacterias, Neumología, Evaluación, Cocos Gram positivos, Azitromicina, Infecciones respiratorias, Infecciones de la piel, Agentes antibacterianos |
| Keyword: | Biology, Medicine, Bacteria, Pneumology, Evaluation, Gram positive cocci, Azithromycin, Respiratory infections, Skin infections, Antibacterial agents |
| Full text: | Texto completo (Ver HTML) |
