| Journal: | The brazilian journal of infectious diseases |
| Database: | PERIÓDICA |
| System number: | 000290867 |
| ISSN: | 1413-8670 |
| Authors: | Matida, Luiza Harunari1 Marcopito, Luiz Francisco2 Succi, Regina Celia de Menezes Marques, Heloisa Helena de Souza3 Della Negra, Marinella4 Grangeiro, Alexandre Hearst, Norman5 |
| Institutions: | 1Secretaria de Estado da Saude, STD/AIDS Program, Sao Paulo. Brasil 2Universidade Federal de Sao Paulo, Sao Paulo. Brasil 3Universidade de Sao Paulo, Sao Paulo. Brasil 4Instituto de Doencas Infecciosas, Sao Paulo. Brasil 5University of California, San Francisco, California. Estados Unidos de América |
| Year: | 2004 |
| Season: | Dic |
| Volumen: | 8 |
| Number: | 6 |
| Pages: | 419-423 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Caso clínico |
| English abstract | Brazil was the first developing country to provide free, universal access to antiretroviral treatment for AIDS patients. The Brazilian experience thus provides the first evidence regarding the impact of such treatment on the survival of perinatally acquired AIDS cases in the developing world. MATERIAL AND METHODS: This retrospective cohort study used medical record reviews to examine characteristics and trends in the survival of a representative sample of 914 perinatally acquired AIDS cases in 10 Brazilian cities diagnosed between 1983 and 1998. RESULTS: Survival time increased steadily and substantially. Whereas half of the children died within 20 months of diagnosis at the beginning of the epidemic, 75% of children diagnosed in 1997 and 1998 were still alive after four years of follow-up. CONCLUSIONS: Advances in management and treatment have made a great difference in the survival of Brazilian children with AIDS. These results argue strongly for making such treatment available to children in the entire developing world |
| Disciplines: | Medicina |
| Keyword: | Diagnóstico, Pediatría, Inmunología, SIDA, Transmisión perinatal, Terapia antirretroviral, Sobrevivencia, Niños |
| Keyword: | Medicine, Diagnosis, Pediatrics, AIDS, Perinatal transmission, Antiretroviral therapy, Survival, Children, Immunology |
| Full text: | Texto completo (Ver HTML) |
