Improving survival among Brazilian children with perinatally-acquired AIDS



Título del documento: Improving survival among Brazilian children with perinatally-acquired AIDS
Revista: The brazilian journal of infectious diseases
Base de datos: PERIÓDICA
Número de sistema: 000290867
ISSN: 1413-8670
Autores: 1
2

3
4

5
Instituciones: 1Secretaria de Estado da Saude, STD/AIDS Program, Sao Paulo. Brasil
2Universidade Federal de Sao Paulo, Sao Paulo. Brasil
3Universidade de Sao Paulo, Sao Paulo. Brasil
4Instituto de Doencas Infecciosas, Sao Paulo. Brasil
5University of California, San Francisco, California. Estados Unidos de América
Año:
Periodo: Dic
Volumen: 8
Número: 6
Paginación: 419-423
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Caso clínico
Resumen en inglés Brazil was the first developing country to provide free, universal access to antiretroviral treatment for AIDS patients. The Brazilian experience thus provides the first evidence regarding the impact of such treatment on the survival of perinatally acquired AIDS cases in the developing world. MATERIAL AND METHODS: This retrospective cohort study used medical record reviews to examine characteristics and trends in the survival of a representative sample of 914 perinatally acquired AIDS cases in 10 Brazilian cities diagnosed between 1983 and 1998. RESULTS: Survival time increased steadily and substantially. Whereas half of the children died within 20 months of diagnosis at the beginning of the epidemic, 75% of children diagnosed in 1997 and 1998 were still alive after four years of follow-up. CONCLUSIONS: Advances in management and treatment have made a great difference in the survival of Brazilian children with AIDS. These results argue strongly for making such treatment available to children in the entire developing world
Disciplinas: Medicina
Palabras clave: Diagnóstico,
Pediatría,
Inmunología,
SIDA,
Transmisión perinatal,
Terapia antirretroviral,
Sobrevivencia,
Niños
Keyword: Medicine,
Diagnosis,
Pediatrics,
AIDS,
Perinatal transmission,
Antiretroviral therapy,
Survival,
Children,
Immunology
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