| Journal: | The brazilian journal of infectious diseases |
| Database: | PERIÓDICA |
| System number: | 000290640 |
| ISSN: | 1413-8670 |
| Authors: | Pereira, Silvia Regina Ferreira Goncalves1 Guimaraes, Maria Angelica Arpon Neto, Leonardo V Segenreich, Daniel Varella, Rafael Brandao Chagas, Vera Lucia Antunes Camara, Fernando Portela |
| Institutions: | 1Universidade Federal do Rio de Janeiro, Instituto de Microbiologia "Paulo de Goes", Rio de Janeiro. Brasil |
| Year: | 2001 |
| Season: | Ago |
| Volumen: | 5 |
| Number: | 4 |
| Pages: | 183-191 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Experimental, analítico |
| English abstract | Two different procedures for inoculation of HSV on corneas of BALB/c mice were evaluated. The first was by the use of HSV suspensions directly on the corneas and the other was after corneal scarification. Animals by this later method presented greater morbidity and mortality than those of first group, suggesting that inoculation of HSV without scarification of the cornea should be the method of choice for the study of HSV ophthalmic infection. This model showed also be an efficient experimental system to testing antiviral drugs |
| Disciplines: | Biología, Medicina |
| Keyword: | Mamíferos, Virus, Oftalmología, Virus del herpes simple, Inoculación, Modelo murino |
| Keyword: | Biology, Medicine, Mammals, Virus, Ophthalmology, Herpes simplex virus, Inoculation, Murine model |
| Full text: | Texto completo (Ver HTML) |
