| Revista: | The brazilian journal of infectious diseases |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000290640 |
| ISSN: | 1413-8670 |
| Autores: | Pereira, Silvia Regina Ferreira Goncalves1 Guimaraes, Maria Angelica Arpon Neto, Leonardo V Segenreich, Daniel Varella, Rafael Brandao Chagas, Vera Lucia Antunes Camara, Fernando Portela |
| Instituciones: | 1Universidade Federal do Rio de Janeiro, Instituto de Microbiologia "Paulo de Goes", Rio de Janeiro. Brasil |
| Año: | 2001 |
| Periodo: | Ago |
| Volumen: | 5 |
| Número: | 4 |
| Paginación: | 183-191 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental, analítico |
| Resumen en inglés | Two different procedures for inoculation of HSV on corneas of BALB/c mice were evaluated. The first was by the use of HSV suspensions directly on the corneas and the other was after corneal scarification. Animals by this later method presented greater morbidity and mortality than those of first group, suggesting that inoculation of HSV without scarification of the cornea should be the method of choice for the study of HSV ophthalmic infection. This model showed also be an efficient experimental system to testing antiviral drugs |
| Disciplinas: | Biología, Medicina |
| Palabras clave: | Mamíferos, Virus, Oftalmología, Virus del herpes simple, Inoculación, Modelo murino |
| Keyword: | Biology, Medicine, Mammals, Virus, Ophthalmology, Herpes simplex virus, Inoculation, Murine model |
| Texto completo: | Texto completo (Ver HTML) |
