Evaluation of the secretory immunoglobulin A levels in the colostrum and milk of mothers of term and pre-trerm newborns



Document title: Evaluation of the secretory immunoglobulin A levels in the colostrum and milk of mothers of term and pre-trerm newborns
Journal: The brazilian journal of infectious diseases
Database: PERIÓDICA
System number: 000290895
ISSN: 1413-8670
Authors: 1




2
Institutions: 1Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte. Brasil
2Universidade Estadual de Campinas, Campinas, Sao Paulo. Brasil
Year:
Season: Oct
Volumen: 9
Number: 5
Pages: 357-362
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Experimental, analítico
English abstract To determine and to compare the levels of secretory immunoglobulin A in samples of colostrum and milk of mothers of term and preterm neonates. The levels of secretory immunoglobulin A of 10 mothers of term neonates and 10 mothers of preterm neonates were determined from 5mL of colostrum or milk collected on the 1st, 4th, 10th and 15th days of the puerperal period, using the radial immunodifusion technique. We employed anamnesis, as well as physical and gynecological exams in women in the puerperal period. All the patients were attended at the Januário Cicco Maternity College. The secretory immunoglobulin A levels were significantly higher in the colostrum and milk of mothers of preterm neonates when compared with the levels found in colostrum and milk of mothers of term neonates (Mann-Whitney test, p<0.0001). There was a significant decline in the secretory immunoglobulin A levels of the colostrum and milk of the mothers of term and preterm neonates during the four periods (Kruskal-Wallis test, p<00001). The secretory immunoglobulin A levels in colostrum and milk of mothers of preterm neonates were significantly higher than in the mothers of term neonates, demonstrating immunological adaptation in preterm neonate breast-feeding
Disciplines: Medicina
Keyword: Inmunología,
Inmunoglobulina A (IgA),
Leche materna,
Calostro,
Neonatos
Keyword: Medicine,
Immunoglobulin A,
Breast milk,
Calostrum,
Neonates,
Immunology
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