| Journal: | The brazilian journal of infectious diseases |
| Database: | PERIÓDICA |
| System number: | 000290671 |
| ISSN: | 1413-8670 |
| Authors: | Sader, Helio S1 Cereda, Rosangela F2 Jones, Ronald N3 Sejas, Lilian Machado, Antonia M4 Zanatta, Yara P Rego, Sinaida T.M.S5 Medeiros, Eduardo A.S |
| Institutions: | 1Universidade Federal de Sao Paulo, Divisao de Doencas Infecciosas, Sao Paulo. Brasil 2Universidade Federal de Sao Paulo, Laboratório Especial de Microbiologia Clinica, Sao Paulo. Brasil 3University of Iowa, College of Medicine, Iowa City, Iowa. Estados Unidos de América 4Hospital Sao Paulo, Laboratorio Central, Sao Paulo. Brasil 5Universidade Federal de Sao Paulo, Comissao de Controle de Infeccao Hospitalar, Sao Paulo. Brasil |
| Year: | 2001 |
| Season: | Feb |
| Volumen: | 5 |
| Number: | 1 |
| Pages: | 40-46 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Caso clínico, analítico |
| English abstract | We report for the first time in Brazil, a patient from whom an Enterococcus faecalis VanA phenotype was isolated. Glycopeptide resistance is not commonly observed in Enterococcus faecalis, so this finding is of great concern since this species is responsible for 90% of enterococcal infections in Brazil. The isolate was recovered from a surveillance rectal swab culture from a patient with acute lymphocytic leukemia (ALL). Identification to the species level was performed by conventional biochemical tests and Vitek GPI cards. Antimicrobial susceptibility testing was evaluated by use of broth microdilution and Etest (AB BIODISK, Solna, Sweden) methods. The isolate was identified as E. faecalis and was considered resistant to both vancomycin (MIC, > 256 mg/mL) and teicoplanin (MIC, 256 mg/mL). The isolate also showed high level resistance to gentamicin and streptomycin (MICs, > 1024 mg/mL), but was considered susceptible to ampicillin (MIC, 4 mg/mL). Although the frequency of enterococcal infections is very low in most Latin America countries, the finding of glycopeptide (VanA) resistance in E. faecalis increases concern about apreading antimicrobial resistance in this region |
| Disciplines: | Medicina |
| Keyword: | Farmacología, Microbiología, Neurología, Enterococcus faecalis, Resistencia antimicrobiana, Trasplante, Médula ósea |
| Keyword: | Medicine, Microbiology, Neurology, Pharmacology, Enterococcus faecalis, Antimicrobial resistance, Transplantation, Bone marrow |
| Full text: | Texto completo (Ver HTML) |
