Deficiency of the eighth component of complement associated with recurrent meningococcal meningitis: case report and literature review



Document title: Deficiency of the eighth component of complement associated with recurrent meningococcal meningitis: case report and literature review
Journal: The brazilian journal of infectious diseases
Database: PERIÓDICA
System number: 000290848
ISSN: 1413-8670
Authors: 1


Institutions: 1Hospital Nossa Senhora da Conceicao, Departamento de Medicina Interna, Porto Alegre, Rio Grande do Sul. Brasil
Year:
Season: Ago
Volumen: 8
Number: 4
Pages: 328-330
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Caso clínico
English abstract The authors report a case of deficiency of the eighth component of complement in a young adult with a history of three episodes of meningitis; one of them proved to be meningococcal. The literature was reviewed and meningitis due to Neisseria meningitidis strains causing disease in complement-deficient and complement-sufficient patients was demonstrated. Meningococcal disease may be the first manifestation of complement deficiency; screening for complement function must be considered for those with invasive meningococcal disease, with posterior evaluation of the components of the terminal pathway of complement
Disciplines: Medicina
Keyword: Microbiología,
Neurología,
Enfermedad meningocócica,
Neisseria meningitidis,
Deficiencia de complemento
Keyword: Medicine,
Microbiology,
Neurology,
Meningococcal disease,
Neisseria meningitidis,
Complement deficiency
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