Journal: | Revista médica de Chile |
Database: | PERIÓDICA |
System number: | 000365882 |
ISSN: | 0034-9887 |
Authors: | Uribe, Reinaldo1 Suárez, Felipe1 Sandoval, Patricio1 Mellado, Patricio1 |
Institutions: | 1Pontificia Universidad Católica de Chile, Facultad de Medicina, Santiago de Chile. Chile |
Year: | 2013 |
Season: | Sep |
Volumen: | 141 |
Number: | 9 |
Pages: | 1211-1215 |
Country: | Chile |
Language: | Español |
Document type: | Revisión bibliográfica |
Approach: | Caso clínico |
English abstract | Anti-GQ1b syndrome includes Miller Fisher Syndrome (MFS), Guillain Barré Syndrome (GBS), Bickerstaff`s brain stem encephalitis (BBE) and Acute Ophtamoplegia (AO). We report four patients aged 16 to 76 years, with anti-GQ1b syndrome. All presented with MFS, one of them evolved to GBS pharyngeal-cervical-brachial variant and other to GBS with BBE. All had a previous history of diarrhea or upper respiratory tract infection. All had positive anti-GQ1b serum antibodies. Both brain magnetic resonance imaging and cerebrospinal fluid analysis were normal. Electrophysiology studies were compatible with a demyelinating disease. Two patients needed airway protection with an orotracheal tube and developed dysautonomia. All four patients were treated with immunomodulation. On the sixth month follow-up, patients had only minimal alterations in the neurological examination |
Disciplines: | Medicina |
Keyword: | Neurología, Terapéutica y rehabilitación, Inmunología, Encefalitis, Gangliósidos, Síndrome de Guillain-Barré, Síndrome de Miller-Fisher, Oftalmoplejía, Inmunomodulación |
Keyword: | Medicine, Neurology, Therapeutics and rehabilitation, Immunology, Encephalitis, Gangliosides, Guillain-Barre syndrome, Miller-Fisher syndrome, Ophthalmoplegia, Immunomodulation |
Full text: | Texto completo (Ver HTML) |