Síndrome anti-GQ1b: Descripción de cuatro pacientes y revisión de la literatura



Título del documento: Síndrome anti-GQ1b: Descripción de cuatro pacientes y revisión de la literatura
Revista: Revista médica de Chile
Base de datos: PERIÓDICA
Número de sistema: 000365882
ISSN: 0034-9887
Autors: 1
1
1
1
Institucions: 1Pontificia Universidad Católica de Chile, Facultad de Medicina, Santiago de Chile. Chile
Any:
Període: Sep
Volum: 141
Número: 9
Paginació: 1211-1215
País: Chile
Idioma: Español
Tipo de documento: Revisión bibliográfica
Enfoque: Caso clínico
Resumen en inglés Anti-GQ1b syndrome includes Miller Fisher Syndrome (MFS), Guillain Barré Syndrome (GBS), Bickerstaff`s brain stem encephalitis (BBE) and Acute Ophtamoplegia (AO). We report four patients aged 16 to 76 years, with anti-GQ1b syndrome. All presented with MFS, one of them evolved to GBS pharyngeal-cervical-brachial variant and other to GBS with BBE. All had a previous history of diarrhea or upper respiratory tract infection. All had positive anti-GQ1b serum antibodies. Both brain magnetic resonance imaging and cerebrospinal fluid analysis were normal. Electrophysiology studies were compatible with a demyelinating disease. Two patients needed airway protection with an orotracheal tube and developed dysautonomia. All four patients were treated with immunomodulation. On the sixth month follow-up, patients had only minimal alterations in the neurological examination
Disciplines Medicina
Paraules clau: Neurología,
Terapéutica y rehabilitación,
Inmunología,
Encefalitis,
Gangliósidos,
Síndrome de Guillain-Barré,
Síndrome de Miller-Fisher,
Oftalmoplejía,
Inmunomodulación
Keyword: Medicine,
Neurology,
Therapeutics and rehabilitation,
Immunology,
Encephalitis,
Gangliosides,
Guillain-Barre syndrome,
Miller-Fisher syndrome,
Ophthalmoplegia,
Immunomodulation
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