| Journal: | Revista médica de Chile |
| Database: | PERIÓDICA |
| System number: | 000405867 |
| ISSN: | 0034-9887 |
| Authors: | Figueroa Reyes, Tatiana1 Sáez, David1 Mansilla, Eloy1 Sánchez, Rodrigo1 Nogales Gaete, Jorge1 Delgado, Iris2 |
| Institutions: | 1Universidad de Chile, Santiago de Chile. Chile 2Universidad del Desarrollo, Santiago de Chile. Chile |
| Year: | 2011 |
| Season: | Sep |
| Volumen: | 139 |
| Number: | 9 |
| Pages: | 1118-1127 |
| Country: | Chile |
| Language: | Español |
| Document type: | Artículo |
| Approach: | Analítico, descriptivo |
| English abstract | Background: The only accepted treatment for acute ischemic stroke is thrombolysis with recombinant tissue plasminogen activator (t-PA). It was implemented in Chile in 1996, although its use was mainly restricted in Chile to private clinics. Recently, at year 2009, we have implemented this treatment in a public hospital. Aim : To describe the results of treatment of acute ischemic stroke with t-PA in a public hospital in Chile. Material and Methods : Prospective analysis of all eligible patients with acute ischemic stroke that were admitted within 4 hours of its onset and had no contraindications for thrombolysis. Results : In an eight months period, a total of 19 intravenous thrombolyses were performed in 12 males and seven females aged 28 to 79 years old. The mean lapse between onset of symptoms and onset of thrombo- lysis was 190 ± 57 min. Results were favorable, according to Rankin and National Institute of Health Stroke scales. Ninety days after treatment, 63% of patients had minimal or absent disability, 26% had moderate disability and only one (5%) had severe disability. One patient had a clinically not significant intracranial hemorrhage and one patient died six days after thrombolysis. Conclusions : These results indicate that thrombolysis can be successfully implemented in Chilean public hospitals. The limitations for its use in this setting are mostly administrative |
| Disciplines: | Medicina |
| Keyword: | Fisiología humana, Sistema cardiovascular, Terapéutica y rehabilitación, Infarto cerebral, Plasminógeno, Terapia trombolítica |
| Keyword: | Medicine, Cardiovascular system, Human physiology, Therapeutics and rehabilitation, Therapeutics and rehabilitation, Plasminogen, Thrombolytic therapy, Brain infarction |
| Full text: | Texto completo (Ver PDF) |
