Revista: | Revista médica de Chile |
Base de datos: | PERIÓDICA |
Número de sistema: | 000405867 |
ISSN: | 0034-9887 |
Autors: | Figueroa Reyes, Tatiana1 Sáez, David1 Mansilla, Eloy1 Sánchez, Rodrigo1 Nogales Gaete, Jorge1 Delgado, Iris2 |
Institucions: | 1Universidad de Chile, Santiago de Chile. Chile 2Universidad del Desarrollo, Santiago de Chile. Chile |
Any: | 2011 |
Període: | Sep |
Volum: | 139 |
Número: | 9 |
Paginació: | 1118-1127 |
País: | Chile |
Idioma: | Español |
Tipo de documento: | Artículo |
Enfoque: | Analítico, descriptivo |
Resumen en inglés | Background: The only accepted treatment for acute ischemic stroke is thrombolysis with recombinant tissue plasminogen activator (t-PA). It was implemented in Chile in 1996, although its use was mainly restricted in Chile to private clinics. Recently, at year 2009, we have implemented this treatment in a public hospital. Aim : To describe the results of treatment of acute ischemic stroke with t-PA in a public hospital in Chile. Material and Methods : Prospective analysis of all eligible patients with acute ischemic stroke that were admitted within 4 hours of its onset and had no contraindications for thrombolysis. Results : In an eight months period, a total of 19 intravenous thrombolyses were performed in 12 males and seven females aged 28 to 79 years old. The mean lapse between onset of symptoms and onset of thrombo- lysis was 190 ± 57 min. Results were favorable, according to Rankin and National Institute of Health Stroke scales. Ninety days after treatment, 63% of patients had minimal or absent disability, 26% had moderate disability and only one (5%) had severe disability. One patient had a clinically not significant intracranial hemorrhage and one patient died six days after thrombolysis. Conclusions : These results indicate that thrombolysis can be successfully implemented in Chilean public hospitals. The limitations for its use in this setting are mostly administrative |
Disciplines | Medicina |
Paraules clau: | Fisiología humana, Sistema cardiovascular, Terapéutica y rehabilitación, Infarto cerebral, Plasminógeno, Terapia trombolítica |
Keyword: | Medicine, Cardiovascular system, Human physiology, Therapeutics and rehabilitation, Therapeutics and rehabilitation, Plasminogen, Thrombolytic therapy, Brain infarction |
Text complet: | Texto completo (Ver PDF) |