| Journal: | Revista médica de Chile |
| Database: | PERIÓDICA |
| System number: | 000448933 |
| ISSN: | 0034-9887 |
| Authors: | Lissarrague, Eugenia Fregeiro, María Sol Binstok, Yemile Barla, Camila Cavani, Manuel Frachia, Felipe Ranero, Sabrina1 Servente, Liliana1 Riva, Eloísa1 |
| Institutions: | 1Universidad de la República, Hospital de Clínicas Dr. Manuel Quintela, Montevideo. Uruguay |
| Year: | 2022 |
| Volumen: | 150 |
| Number: | 2 |
| Pages: | 199-205 |
| Country: | Chile |
| Language: | Español |
| Document type: | Artículo |
| Approach: | Aplicado, descriptivo |
| English abstract | Background: 18F-fluorodesoxyglucose positron emission tomography/ computed tomography (PET-CT) has a high sensitivity and specificity to detect medullary and extramedullary lesions in multiple myeloma (MM). Aim: To describe the findings of PET-CT in extramedullary multiple myeloma (EMM) at diagnosis and at relapse, and correlate its results with clinical variables, response to treatment and survival. Materials and Methods: Review of medical records and PET-CT reports of 39 patients with multiple myeloma (MM) who had at least one PET-CT study, treated between January 1, 2015, and January 1, 2019 at a clinical hospital. Results: The Standard Uptake Values for each hypermetabolic lesion were not described in PET-CT reports. Fifteen patients had an EMM and in eight, without a previous clinical suspicion, PET-TC lead to the diagnosis. The mortality rate in the 39 patients with MM was 46%. Sixty seven percent of deaths occurred in patients with EMM. Conclusions: PET-TC was useful to diagnose EMM. However, a standardization in PETCT reports would be required to unify criteria. As previously reported, EMM had a greater aggressiveness and lower survival |
| Disciplines: | Medicina |
| Keyword: | Neurología, Diagnóstico, Mieloma múltiple, Tomografía por emisión de positrones, Fluorodesoxiglucosa |
| Keyword: | Neurology, Diagnosis, Multiple myeloma, Positron emission tomography, Fluorodeoxyglucose |
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