Aportes de la tomografía por emisión de positrones con 18F-fluorodesoxiglucosa/tomografía computada en el diagnóstico de compromiso extramedular por mieloma múltiple en Uruguay



Título del documento: Aportes de la tomografía por emisión de positrones con 18F-fluorodesoxiglucosa/tomografía computada en el diagnóstico de compromiso extramedular por mieloma múltiple en Uruguay
Revista: Revista médica de Chile
Base de datos: PERIÓDICA
Número de sistema: 000448933
ISSN: 0034-9887
Autors:





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Institucions: 1Universidad de la República, Hospital de Clínicas Dr. Manuel Quintela, Montevideo. Uruguay
Any:
Volum: 150
Número: 2
Paginació: 199-205
País: Chile
Idioma: Español
Tipo de documento: Artículo
Enfoque: Aplicado, descriptivo
Resumen en inglés Background: 18F-fluorodesoxyglucose positron emission tomography/ computed tomography (PET-CT) has a high sensitivity and specificity to detect medullary and extramedullary lesions in multiple myeloma (MM). Aim: To describe the findings of PET-CT in extramedullary multiple myeloma (EMM) at diagnosis and at relapse, and correlate its results with clinical variables, response to treatment and survival. Materials and Methods: Review of medical records and PET-CT reports of 39 patients with multiple myeloma (MM) who had at least one PET-CT study, treated between January 1, 2015, and January 1, 2019 at a clinical hospital. Results: The Standard Uptake Values for each hypermetabolic lesion were not described in PET-CT reports. Fifteen patients had an EMM and in eight, without a previous clinical suspicion, PET-TC lead to the diagnosis. The mortality rate in the 39 patients with MM was 46%. Sixty seven percent of deaths occurred in patients with EMM. Conclusions: PET-TC was useful to diagnose EMM. However, a standardization in PETCT reports would be required to unify criteria. As previously reported, EMM had a greater aggressiveness and lower survival
Disciplines Medicina
Paraules clau: Neurología,
Diagnóstico,
Mieloma múltiple,
Tomografía por emisión de positrones,
Fluorodesoxiglucosa
Keyword: Neurology,
Diagnosis,
Multiple myeloma,
Positron emission tomography,
Fluorodeoxyglucose
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