| Journal: | Revista de saude publica |
| Database: | |
| System number: | 000535731 |
| ISSN: | 0034-8910 |
| Authors: | Tavares, Nayranne Hivina Carvalho1 Coelho, Carolina Gomes2 Barreto, Sandhi M.2 Giatti, Luana2 Araújo, Larissa Fortunato1 |
| Institutions: | 1Universidade Federal do Ceará, Faculdade de Medicina, Fortaleza, Ceará. Brasil 2Universidade Federal de Minas Gerais, Faculdade de Medicina, Belo Horizonte, Minas Gerais. Brasil |
| Year: | 2022 |
| Volumen: | 56 |
| Country: | Brasil |
| Language: | Inglés |
| English abstract | OBJECTIVE To investigate the association between birth weight and bone mineral content (BMC), and whether this relationship differs between men and women. METHODS A total of 10,159 participants from the ELSA-Brasil cohort were eligible for this analysis. The outcome was the z-score of the ratio BMC (kg)/height (m). The exposure was the low birth weight (< 2.5kg). The magnitude of the associations was estimated by mean differences and their respective 95% confidence intervals (95%CI) using linear regression. All analyses were presented for the total population and stratified by sex. RESULTS Most were women (54.98%), and the mean age was 52.72 years (SD ± 6.6). In the crude model, we observed that low birth weight was associated with a lower mean BMC/height z-score, compared to adequate birth weight (mean difference: −0.30; 95%CI: −0.39 to −0.21), and this effect was stronger in men (mean difference: −0.43; 95%CI: −0.56 to −0.30) than in women (mean difference: −0.31; 95%CI: −0.44 to −0.19). After adjusting for age, sex per total population, race/skin color, maternal education, individual education, and current weight, there was a considerable reduction in the magnitude of the association (total population: −0.10; 95%CI: −0.14 to −0.06; men: −0.13; 95%CI: −0.21 to −0.06; women: −0.13; 95%CI: −0.21 to −0.05). CONCLUSION Low birth weight is related to BMC/height z-score in both sexes with no indication of differences by sex. The magnitude of the associations was attenuated after adjustment for the current weight. |
| Keyword: | Bone Density, Birth Weight, Embryonic and Fetal Development, Sex Distribution |
| Full text: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
