| Revista: | Revista de investigación clínica |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000456872 |
| ISSN: | 0034-8376 |
| Autores: | Juárez Rojas, J. Gabriel1 Posadas Romero, Carlos1 Martínez Alvarado, Rocío1 Jorge Galarza, Esteban1 Reyes Barrera, Juan1 Sánchez Lozada, L. Gabriela2 Torres Tamayo, Margarita2 Medina Urrutia, Aída X2 |
| Instituciones: | 1Instituto Nacional de Cardiología Ignacio Chávez, Departamento de Endocrinología, Ciudad de México. México 2Instituto Nacional de Cardiología Ignacio Chávez, Departamento de Nefrología, Ciudad de México. México |
| Año: | 2018 |
| Volumen: | 70 |
| Número: | 6 |
| Paginación: | 301-309 |
| País: | México |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | Background: In subjects without a history of coronary heart disease (CHD), type 2 diabetes mellitus (T2DM) is associated with carotid artery plaques (CAP), which is a better marker than high carotid intima-media thickness (hCIMT) for predicting first or recurrent cardiovascular events. Objective: The objective of this study is to analyze the association of T2DM with CAP and hCIMT in premature CHD patients. Methods: Premature CHD was considered before the age of 55 years in men and before 65 in women. T2DM was defined according to the American Diabetes Association criteria. CAP was defined as a focal structure encroaching the arterial lumen by at least 50% of the surrounding IMT value or with a thickness > 1.5 mm. Results: Among 1196 patients (CHD duration 1.5 years [interquartile range: 0.4-5.6]), 37.2% had T2DM, and 97.8% were on antihypertensive, 94.4% on lipid-lowering, and 97.3% on anti-aggregate treatment. hCIMT prevalence was similar in patients with or without T2DM, whereas CAP prevalence was higher among T2DM patients (17.7% vs. 30.9%; p < 0.001). T2DM showed association with CAP, independently of CHD evolution and glycemic control (odds ratio: 1.57; 95% confidence interval: 1.09-2.26). Conclusions: T2DM has an independent association with CAP. Early detection of recurrent cardiovascular events, with CAP identification, could be useful to prevent complications in patients with CHD |
| Disciplinas: | Medicina |
| Palabras clave: | Sistema cardiovascular, Endocrinología, Diabetes mellitus, Grosor arterial, Carótida, Aterosclerosis, Enfermedad coronaria |
| Keyword: | Cardiovascular system, Endocrinology, Diabetes mellitus, Arterial thickness, Carotid artery, Atherosclerosis, Coronary diseases |
| Texto completo: | https://www.medigraphic.com/pdfs/revinvcli/nn-2018/nn186f.pdf |
