Small Airway Disease in COPD Associated to Biomass Exposure



Título del documento: Small Airway Disease in COPD Associated to Biomass Exposure
Revista: Revista de investigación clínica
Base de datos: PERIÓDICA
Número de sistema: 000454206
ISSN: 0034-8376
Autores: 1
2
1
2
3
Instituciones: 1Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Departamento de Investigación en Tabaquismo y EPOC, Ciudad de México. México
2Universidad de la Sabana, Departamento de Investigación, Bogotá. Colombia
3Fundación Clínica Médica Sur, Departamento de Medicina Respiratoria, Ciudad de México. México
Año:
Periodo: Ene-Feb
Volumen: 71
Número: 1
Paginación: 70-78
País: México
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Analítico, descriptivo
Resumen en inglés Chronic obstructive pulmonary disease (COPD) is a complex and heterogeneous entity that may result from different causative agents and risk factors and may follow diverse clinical courses, including COPD secondary to biomass smoke exposure. At present, this phenotype is becoming more important for two reasons: first, because at least almost half of the world’s population is exposed to biomass smoke, and second, because the possibility of it being diagnosed is increasing. Biomass smoke exposure COPD affects primarily women and is related with insults to the airways occurred during early life. Although constituents of biomass smoke and tobacco smoke are similar, the physiopathological changes they induce differ depending not only on the chemical composition (related with the type of fuel used) but also on the particle size and the inhalation pattern. Evidence has shown that biomass smoke exposure affects the airway, predominantly the small airways causing anthracofibrosis and peribronchiolar fibrosis changes that will clinically translate into chronic bronchitis symptoms, with a high impact on the quality of life. In this review, we focus especially on the main epidemiological and clinical differences between COPD secondary to biomass exposure and COPD caused by tobacco exposure
Disciplinas: Medicina
Palabras clave: Neumología,
Tabaquismo,
Enfermedad de las vias aéreas,
Enfermedad pulmonar obstructiva crónica (EPOC)
Keyword: Pneumology,
Smoking,
Airways disease,
Chronic obstructive pulmonary disease (COPD)
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