| Journal: | Revista de investigación clínica |
| Database: | PERIÓDICA |
| System number: | 000452952 |
| ISSN: | 0034-8376 |
| Authors: | Gómez Ortiz, David1 Garza Gangemi, Adrián M1 Oropeza Aguilar, Mariano1 Rangel Suárez, Sergio2 Espinosa Cruz, Verónica2 Villegas Hernández, Antonio C2 Martínez Martínez, Ricardo2 Castillejos Molina, Ricardo A1 |
| Institutions: | 1Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Departamento de Urología, Ciudad de México. México 2Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Departamento de Radiología, Ciudad de México. México |
| Year: | 2022 |
| Season: | Jul-Ago |
| Volumen: | 74 |
| Number: | 4 |
| Pages: | 212-218 |
| Country: | México |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Analítico, descriptivo |
| English abstract | Multiparametric magnetic resonance imaging improves the performance of prostate cancer (PCa) diagnostics through a better selection of patients. Objectives: The aim of the study was to study the detection rate (DR) of systematic and targeted cognitive biopsies in a cohort with the previous negative systematic biopsies. A secondary objective was to describe the value of prostate-specific antigen density (PSAd) in the detection of clinically significant PCa (CSPCa). Methods: We designed a prospective, single-center, and comparative study to determine the DR of systematic and targeted cognitive biopsies. The clinical and pathological characteristics of each patient were described. Results: A total of 111 patients with Prostate Imaging Reporting and Data System lesions > 3 were included in the study. PCa was detected in 41.4% (46 of 111 patients); 42 (91.3%) were detected by systematic biopsy and 30 (65.2%) by targeted biopsy. CSPCa was detected in 26 (23.4%), 23 (88.5%) by systematic biopsy, and 21 (76.9%) by targeted biopsy. PSAd > 0.15 was directly associated with CSPCa. Conclusion: The detection of PCa by systematic biopsy in this series was higher than 80%; hence, its routine use should not be replaced by targeted biopsy, since it continues to be the cornerstone of the diagnosis in patients with prior negative biopsies |
| Disciplines: | Medicina |
| Keyword: | Oncología, Urología, Diagnóstico, Cáncer, Próstata, Técnicas de diagnóstico, Biopsia prostática transrrectal, Resonancia magnética multiparamétrica |
| Keyword: | Oncology, Urology, Diagnosis, Cancer, Prostate, Diagnostic techniques, Transrectal prostatic biopsy, Multiparametric magnetic resonance |
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