| Revista: | Revista de investigación clínica |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000455363 |
| ISSN: | 0034-8376 |
| Autores: | Liang, Tian1 Liu, Min1 Wu, Chengyu1 Zhang, Qing1 Lu, Lei1 Wang, Zhongliang1 |
| Instituciones: | 1Nanjing University of Chinese Medicine, Xuzhou City Hospital of Traditional Chinese Medicine, Xuzhou, Jiangsu. China |
| Año: | 2017 |
| Periodo: | May-Jun |
| Volumen: | 69 |
| Número: | 3 |
| Paginación: | 139-145 |
| País: | México |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | To explore risk factors for no-reflow phenomenon after percutaneous coronary intervention in patients with acute coronary syndrome. Methods: A total of 733 acute myocardial infarction patients with persistent ischemic chest pain within 12 or 12-24 hours after onset received emergency percutaneous coronary intervention. Patients were divided into a normal reflow group and a no-reflow group, according to TIMI grading and myocardial blush grading after percutaneous coronary intervention. Related risk factors were analyzed. Results: The incidence of no-reflow phenomenon after percutaneous coronary intervention was 16.1%. Univariate analysis showed that, compared with the normal reflow group, the no-reflow group was older, reperfusion time was significantly longer, preoperative systolic pressure was lower, troponin peak was higher, and creatine kinase enzyme peak was higher (p < 0.05). The proportions of preoperative cardiac function Killip grade ≥ 2 and number of patients using preoperative intra-aortic balloon pump were significantly different (p < 0.05). Multivariate logistic regression analysis showed that age > 65 years (OR: 1.471; 95% CI: 1.462-1.492; p = 0.007), reperfusion time > 6 hours (OR: 1.274; 95% CI: 1.164-1.405; p = 0.001), low systolic pressure at admission (< 100 mmHg) (OR: 1.918; 95% CI: 1.017-3.897; p = 0.004), intra-aortic balloon pump use before percutaneous coronary intervention (OR: 1.949; 95% CI: 1.168-3.253; p = 0.011), low TIMI grade (≤ 1) before percutaneous coronary intervention (OR: 1.100; 95% CI: 1.086-1.257; p < 0.01), high thrombus load (OR: 1.274; 95% CI: 1.423-2.761; p = 0.030), and long target lesion (OR: 1.948; 95% CI: 1.908-1.990; p = 0.019) were independent risk factors. Conclusions: No-reflow phenomenon after percutaneous coronary intervention in patients with acute coronary syndrome was affected by complicated pathological factors |
| Disciplinas: | Medicina |
| Palabras clave: | Sistema cardiovascular, Síndrome coronario agudo, Infarto al miocardio, Intervención coronaria percutánea, Fenómeno de no reflujo |
| Keyword: | Cardiovascular system, Acute coronary syndrome, Myocardial infarction, Percutaneous coronary intervention, Non reflow phenomenon |
| Texto completo: | https://www.medigraphic.com/pdfs/revinvcli/nn-2017/nn173b.pdf |
