| Revista: | Revista de investigación clínica |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000455379 |
| ISSN: | 0034-8376 |
| Autores: | Aguilar Navarro, Sara G1 Mimenza Alvarado, Alberto J1 Avila Funes, José Alberto1 Juárez Cedillo, Teresa2 Bernal López, Carolina1 Hernández Favela, Celia G3 |
| Instituciones: | 1Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Departamento de Geriatría, Ciudad de México. México 2Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Ciudad de México. México 3Universidad Autónoma de Coahuila, Facultad de Medicina, Torreón, Coahuila. México |
| Año: | 2017 |
| Periodo: | Ene-Feb |
| Volumen: | 69 |
| Número: | 1 |
| Paginación: | 33-39 |
| País: | México |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | Mild cognitive impairment (MCI) is considered a clinical stage between normal cognitive aging and dementia. The clinical course of MCI is heterogeneous, with a significant number of cases progressing to dementia or reverting back to normal. Objective: To determine the predictors of conversion from mild cognitive impairment to dementia among Mexican older adults. Materials and Methods: A sample of 175 persons underwent clinical and neuropsychological evaluation to establish mild cognitive impairment diagnosis. These patients were followed-up for a mean 3.5 years. Results: Mean age was 81.7 (± 6.9) years, 57% were women, and mean education level was 9.5 (± 6.1) years. Sixty-one percent of mild cognitive impairment participants progressed to dementia. Multivariate Cox regression analysis showed that progression to dementia was associated with age (HR: 4.95; 95% CI: 1.96-12.46; p = 0.001), low education level (HR: 5.81; 95% CI: 1.90-7.78; p < 0.002), history of stroke (HR: 3.92; 95% CI: 1.37-11.16; p < 0.012) and cognitive decline (HR: 1.31; 95% CI: 1.18-1.45; p = 0.000). Conclusions: Age, poor education, cognitive decline, and a history of stroke were predictors of conversion to dementia. The identification and control of modifiable risk factors could influence conversion to dementia |
| Disciplinas: | Medicina |
| Palabras clave: | Psiquiatría, Geriatría, Ancianos, Disfunción cognitiva, Factores pronósticos, Demencia |
| Keyword: | Psychiatry, Geriatrics, Aged, Cognitive impairment, Prognostic factors, Dementia |
| Texto completo: | https://www.medigraphic.com/pdfs/revinvcli/nn-2017/nn171e.pdf |
