| Revista: | Revista de investigación clínica |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000456873 |
| ISSN: | 0034-8376 |
| Autores: | Vidal Mayo, José de Jesús1 Olivas Martínez, Antonio1 Pérez Díaz, Iván1 López Navarro, Juan M1 Sánchez Landa, Elizabet2 Carrillo Maravilla, Eduardo1 Portillo González, Martha1 Fagundo Sierra, Reynerio1 Leal Villareal, Mario Andrés de Jesús1 |
| Instituciones: | 1Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México. México 2Instituto Tecnológico y de Estudios Superiores de Monterrey, Campus Ciudad de México, Ciudad de México. México |
| Año: | 2018 |
| Volumen: | 70 |
| Número: | 6 |
| Paginación: | 310-318 |
| País: | México |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | Urine osmolarity (OsmU) is the gold standard for the evaluation of the kidney’s urine concentration capacity; nevertheless, urinary density (UD) is often used as a surrogate for its estimation. Objective: The objective of this study was to analyze the accuracy of UD in estimating OsmU. Materials and Methods: A transversal study including patients with simultaneous determination of UD measured with refractometry and OsmU measured by osmometer (OsmUm). We multiplied the last two digits of the UD by 35, 30, 32, 33.5, and 40 to estimate OsmU; the estimates were considered precise if the value was ± 30 mOsm/kg from the OsmUm. A Bland–Altman analysis was conducted. Results: Among 205 patients, there was no difference between OsmUm and the estimated form when using a factor of 33.5 (p = 0.578). When analyzing by the absence or presence of proteinuria and/or glycosuria, there were no differences when using the factors 35 (p = 0.844) and 32 with adjusted UD (p = 0.898). In the linear correlation analysis, values for Pearson’s r = 0.788 and r2 = 0.621 were obtained (p < 0.001). The areas under the curve obtained by the receiver operating characteristics curves to estimate urine osmolarity values < 100 and > 600 mOsm/kg were > 0.90. Conclusion: The estimation of the OsmU from UD showed adequate perf rmance. If an osmometer is unavailable, we recommend using the factor 35 for clean samples and 32 with adjusted UD for samples with proteinuria and/or glycosuria |
| Disciplinas: | Medicina |
| Palabras clave: | Nefrología, Diagnóstico, Pruebas de función renal, Hiponatremia, Densidad urinaria, Osmolaridad urinaria |
| Keyword: | Nephrology, Diagnosis, Renal function tests, Hyponatremia, Urinary density, Urinary osmolarity |
| Texto completo: | https://www.medigraphic.com/pdfs/revinvcli/nn-2018/nn186g.pdf |
