Identificação de variantes de hemoglobina em doadores de sangue



Document title: Identificação de variantes de hemoglobina em doadores de sangue
Journal: Revista brasileira de hematologia e hemoterapia
Database: PERIÓDICA
System number: 000306016
ISSN: 1516-8484
Authors: 1
1
Institutions: 1Hemocentro de Sao Jose do Rio Preto, Sao Jose do Rio Preto, Sao Paulo. Brasil
Year:
Season: Ene-Mar
Volumen: 26
Number: 1
Pages: 57-59
Country: Brasil
Language: Portugués
Document type: Correspondencia
Approach: Descriptivo
English abstract Hemoglobinopathies are the most common genetic diseases and affect a great number of individuals in the world, with diverse clinical complications ranging from the almost unnoticeable to lethal consequences. In Brazil the occurrence of hemoglobinopathies is very frequent and influenced by the ethnical groups that are the basis of populations in different regions. The phenotype may be influenced by environmental and genetic factors and by migration. An understanding of these genetic diseases is important for the health and quality of life of the population. In this work we assessed the presence of Hb variants in blood donors from São José do Rio Preto and region, and we observed the occurrence of variants including Hb S and Hb C but in particular the so-called "Like" variants. Good determination of the forms of variant hemoglobins is very important to give better guidance to blood donors and their families, and to improve the quality of blood transfusion
Disciplines: Medicina
Keyword: Hematología,
Salud pública,
Variantes,
Hemoglobina,
Donadores de sangre
Keyword: Medicine,
Hematology,
Public health,
Variants,
Hemoglobin,
Blood donors
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