| Journal: | Quimica nova |
| Database: | PERIÓDICA |
| System number: | 000313436 |
| ISSN: | 0100-4042 |
| Authors: | Macedo-Junior, Fernando Cesar de1 |
| Institutions: | 1Universidade Estadual de Campinas, Instituto de Quimica, Campinas, Sao Paulo. Brasil |
| Year: | 2007 |
| Season: | Feb |
| Volumen: | 30 |
| Number: | 1 |
| Pages: | 116-124 |
| Country: | Brasil |
| Language: | Portugués |
| Document type: | Artículo |
| Approach: | Analítico, descriptivo |
| English abstract | During the last five decades, as a result of an interaction between natural product chemistry, synthetic organic chemistry, molecular biology and spectroscopy, scientists reached an extraordinary level of comprehension about the natural processes by which living organisms build up complex molecules. In this context, 13C nuclear magnetic resonance spectroscopy, allied with isotopic labeling, played a determinant role. Nowadays, the widespread use of modern NMR techniques allows an even more detailed picture of the biochemical steps by accurate manipulation of the atomic nuclei. This article focuses on the development of such techniques and their impact on biosynthetic studies |
| Disciplines: | Química |
| Keyword: | Bioquímica, Vías biosintéticas, Productos naturales, Marcaje isotópico, Resonancia magnética nuclear |
| Keyword: | Chemistry, Biochemistry, Biosynthetic ways, Natural products, Isotopic labeling, Nuclear magnetic resonance |
| Full text: | Texto completo (Ver HTML) |
