Cannabinoids, anxiety, and the periaqueductal gray



Document title: Cannabinoids, anxiety, and the periaqueductal gray
Journal: Psychology & neuroscience
Database: CLASE
System number: 000322745
ISSN: 1983-3288
Authors: 1
2
Institutions: 1Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais. Brasil
2Universidade Federal de Minas Gerais, Instituto de Ciencias Biologicas, Belo Horizonte, Minas Gerais. Brasil
Year:
Volumen: 3
Number: 1
Pages: 39-42
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Analítico
English abstract The use of Cannabis sativa by humans dates back several thousand years, for both its psychotomimetic and potential medicinal properties. As scientific research methods developed, the cannabinoids present in this herb were characterized, as well as their complex interface with the human central nervous system, provided by the activation of specific receptors. The subsequent description of an endogenous cannabinoid system in the mammalian brain shifted the notion of cannabis as a recreational drug to a therapeutic alternative for psychiatric disorders. However, the neuroanatomical sites mediating its effects have remained uncertain. In the present paper, we review recent data suggesting that the midbrain periaqueductal gray may be a structure involved in the anxiolytic-like effects of cannabinoids
Disciplines: Medicina,
Psicología
Keyword: Toxicología,
Cannabis,
Mariguana,
Ansiedad,
Materia gris periacueductal,
Drogadicción
Full text: Texto completo (Ver PDF)