| Journal: | Phyton |
| Database: | PERIÓDICA |
| System number: | 000326974 |
| ISSN: | 0031-9457 |
| Authors: | Manilal, A1 Sujith, S1 Selvin, J1 Shakir, C1 Seghal Kiran, G2 |
| Institutions: | 1Bharathidasan University, Department of Biotechnology, Tiruchirapalli, Tamil Nadu. India 2Bharathidasan University, Department of Microbiology, Tiruchirapalli, Tamil Nadu. India |
| Year: | 2009 |
| Volumen: | 78 |
| Pages: | 161-166 |
| Country: | Argentina |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Experimental, aplicado |
| Spanish abstract | La propiedad antibacteriana del alga roja, Falkenbergia hillebrandii (Born), recogida en la costa suroeste de la India (Océano Índico), fue evaluada contra tres cepas de patógenos humanos resistentes a varias drogas. Con este propósito se utilizaron cuatro solventes diferentes: acetato de etilo, diclorometano, metanol y un amortiguador (buffer) de fosfato salino (PBS). Las muestras secas extraídas con metanol mostraron una actividad antimicrobiana mayor y más amplia en comparación a otros disolventes. Sin embargo, los extractos de PBS no mostraron actividad antibacteriana. Los principios bioactivos del alga roja, F. hillebrandii fueron fraccionados y purificados utilizando diferentes sistemas de cromatografía de fase inversa incluyendo HPLC y GC-MS. El análisis reveló que el metabolito más abundante fue el ácido oleico (51,33%), seguido por el ácido n-hexadecanoico (42%) |
| English abstract | The antibacterial property of the red algae, Falkenbergia hillebrandii (Born) collected from the southwest coast of India (Indian Ocean) was evaluated against three multidrug resistant human pathogens. Four different solvents: ethyl acetate, dichloromethane, methanol and phosphate buffer saline (PBS) were used with this purpose. Dried samples extracted with methanol showed broadest and highest antimicrobial activity when compared to other solvents. However, PBS extract showed no antibacterial activity. The highly active compounds red alga, F. hillebrandii were fractionated and purified using different chromatographic systems, including reverse phase HPLC and GCMS. The analysis revealed that the most abundant metabolite was the oleic acid (51.33%) followed by n-hexadecanoic acid (42%) |
| Disciplines: | Biología |
| Keyword: | Algas, Microbiología, Actividad antibacteriana, Compuestos bioactivos, Falkenbergia hillebrandii |
| Keyword: | Biology, Algae, Microbiology, Antibacterial activity, Bioactive compounds, Falkenbergia hillebrandii |
| Full text: | Texto completo (Ver PDF) |
