| Journal: | Memorias do Instituto Oswaldo Cruz |
| Database: | PERIÓDICA |
| System number: | 000420028 |
| ISSN: | 0074-0276 |
| Authors: | Mendonça, Marcos César Lima de1 Mares-Guia, Maria Angelica1 Rodrigues, Cintia Damasceno dos Santos1 Santos, Carolina Cardoso dos1 Chalhoub, Flavia Lowen Levy1 Araújo, Eliane Saraiva Machado1 Chieppe, Alexandre Otávio2 Nogueira, Rita Maria Ribeiro1 Filippis, Ana Maria Bispo de1 |
| Institutions: | 1Instituto Oswaldo Cruz, Laboratorio de Flavivirus, Rio de Janeiro. Brasil 2Secretaria de Estado de Saude do Rio de Janeiro, Rio de Janeiro. Brasil |
| Year: | 2018 |
| Volumen: | 113 |
| Number: | 8 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Experimental, aplicado |
| English abstract | The dengue virus (DENV), of the genus Flavivirus (Flaviviridae), has four antigenically distinct serotypes, of which DENV-3 is classified into five genotypes. Here, we describe the detection of DENV-3 genotype I in sera of a Brazilian patient travelling from Singapore to Rio de Janeiro, Brazil, by using multiplex real-time RT-PCR, DNA sequencing of the whole envelope protein gene, and phylogenetic analysis. The virus shares ancestry with those identified in Bali, Indonesia, in 2015. It is possible that arboviruses such as Chikungunya ECSA genotype, DENV-4 genotype I, and Zika were introduced in Brazil from other continents during the multiple international events hosted by the country over the last four years, including World Youth Day, the Soccer World Cup, and the Summer Olympics |
| Disciplines: | Medicina |
| Keyword: | Virus, Genética, Virus del dengue, Secuencia génica, Genotipificación |
| Keyword: | Virus, Genetics, Dengue virus, Gene sequence, Genotyping |
| Full text: | Texto completo (Ver HTML) |
