Imported case of Dengue virus 3 genotype I in Rio de Janeiro state, Brazil



Título del documento: Imported case of Dengue virus 3 genotype I in Rio de Janeiro state, Brazil
Revue: Memorias do Instituto Oswaldo Cruz
Base de datos: PERIÓDICA
Número de sistema: 000420028
ISSN: 0074-0276
Autores: 1
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Instituciones: 1Instituto Oswaldo Cruz, Laboratorio de Flavivirus, Rio de Janeiro. Brasil
2Secretaria de Estado de Saude do Rio de Janeiro, Rio de Janeiro. Brasil
Año:
Volumen: 113
Número: 8
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Experimental, aplicado
Resumen en inglés The dengue virus (DENV), of the genus Flavivirus (Flaviviridae), has four antigenically distinct serotypes, of which DENV-3 is classified into five genotypes. Here, we describe the detection of DENV-3 genotype I in sera of a Brazilian patient travelling from Singapore to Rio de Janeiro, Brazil, by using multiplex real-time RT-PCR, DNA sequencing of the whole envelope protein gene, and phylogenetic analysis. The virus shares ancestry with those identified in Bali, Indonesia, in 2015. It is possible that arboviruses such as Chikungunya ECSA genotype, DENV-4 genotype I, and Zika were introduced in Brazil from other continents during the multiple international events hosted by the country over the last four years, including World Youth Day, the Soccer World Cup, and the Summer Olympics
Disciplinas: Medicina
Palabras clave: Virus,
Genética,
Virus del dengue,
Secuencia génica,
Genotipificación
Keyword: Virus,
Genetics,
Dengue virus,
Gene sequence,
Genotyping
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