| Journal: | Memorias do Instituto Oswaldo Cruz |
| Database: | PERIÓDICA |
| System number: | 000446389 |
| ISSN: | 0074-0276 |
| Authors: | Reis, Lisiane Lappe dos1 Silva, Túllio Romão Ribeiro da1 Braga, Francisco Carlos de Oliveira1 Nascimento, Naara Macedo do1 Menezes, Katia Maria Lima de1 Nava, Alessandra Ferreira Dales1 Lima, Natália Aparecida de Souza2 Vicente, Ana Carolina Paulo3 |
| Institutions: | 1Fundacao Oswaldo Cruz, Instituto Leonidas e Maria Deane, Manaus, Amazonas. Brasil 2Superintendencia do Ibama no Amazonas, Centro de Triagem de Animais Silvestres, Manaus, Amazonas. Brasil 3Fundacao Oswaldo Cruz, Instituto Oswaldo Cruz, Rio de Janeiro. Brasil |
| Year: | 2021 |
| Volumen: | 116 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Analítico, descriptivo |
| English abstract | BACKGROUND Giardia duodenalis is a protozoan parasite that infects humans and other mammals and causes giardiasis worldwide. Giardia is genotyped into eight assemblages (A-H), with assemblages A and B considered zoonotic. OBJECTIVES The aim of this study was to determine the assemblages of G. duodenalis from individuals living in rural and urban areas of the Amazonas State. METHODS 103 human faecal specimens microscopically positive for the presence of Giardia obtained from four municipalities in Amazonas and four animal faecal specimens were genotyped based on the sequences of two genes, triosephosphate isomerase (TPI) and β-giardin (BG). FINDINGS In humans, assemblage A was the most represented with the identification of sub-assemblages AI, AII and AIII based on BG and sub-assemblages AI and AII based on TPI. Similarly, there is a diversity of sub-assemblage B considering BG (B and BIII) and TPI (B, BIII and BIV). In addition, we characterised homogeneous and heterogeneous genotypes comprising assemblages/sub-assemblages A and B in individuals from urban and rural areas. Here, for the first time, it was genotyped Giardia that infects animals from the Brazilian Amazon region. We identified sub-assemblage AI in one Ateles paniscus and two Felis catus and sub-assemblage BIV in one Lagothrix cana. MAIN CONCLUSIONS Therefore, humans and animals from the urban and rural Amazon share Giardia genotypes belonging to assemblages A and B, which are found in cosmopolitan regions around the world |
| Disciplines: | Medicina |
| Keyword: | Salud pública, Zoonosis, Giardiasis, Epidemiología, Mecanismos de infección, Genotipos, Giardia duodenalis |
| Keyword: | Public health, Zoonoses, Giardiasis, Epidemiology, Infection mechanisms, Genotypes, Giardia duodenalis |
| Full text: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
