Genomics and functional genomics in Leishmania and Trypanosoma cruzi: statuses, challenges and perspectives
Document title: Genomics and functional genomics in Leishmania and Trypanosoma cruzi: statuses, challenges and perspectives
Journal: Memorias do Instituto Oswaldo Cruz
Database: PERIÓDICA
System number: 000446521
ISSN: 0074-0276
Authors: 1
2
3
Institutions: 1Universidade Federal de Minas Gerais, Departamento de Parasitologia, Belo Horizonte, Minas Gerais. Brasil
2Universidade Federal de Minas Gerais, Departamento de Bioquimica e Imunologia, Belo Horizonte, Minas Gerais. Brasil
3Universidade de Sao Paulo, Faculdade de Medicina de Ribeirao Preto, Ribeirao Preto, Sao Paulo. Brasil
Year:
Volumen: 116
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Analítico, descriptivo
English abstract The availability of Trypanosomatid genomic data in public databases has opened myriad experimental possibilities that have contributed to a more comprehensive understanding of the biology of these parasites and their interactions with hosts. In this review, after brief remarks on the history of the Trypanosoma cruzi and Leishmania genome initiatives, we present an overview of the relevant contributions of genomics, transcriptomics and functional genomics, discussing the primary obstacles, challenges, relevant achievements and future perspectives of these technologies
Disciplines: Biología
Keyword: Protozoarios,
Genética,
Genómica funcional,
Transcriptómica,
Leishmania,
Trypanosoma cruzi
Keyword: Protozoa,
Genetics,
Leishmania,
Trypanosoma cruzi,
Transcriptomics,
Functional genomics
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