| Journal: | lRevista médica de Chile |
| Database: | PERIÓDICA |
| System number: | 000449354 |
| ISSN: | 0034-9887 |
| Authors: | Navarro, Francisco1 Gaete, María Inés2 Riquoir, Christophe2 Azócar, Cristóbal1 Pimentel, Fernando1 |
| Institutions: | 1Pontificia Universidad Católica de Chile, Hospital Clínico, Santiago de Chile. Chile 2Pontificia Universidad Católica de Chile, Facultad de Medicina, Santiago de Chile. Chile |
| Year: | 2021 |
| Season: | Ago |
| Volumen: | 149 |
| Number: | 8 |
| Pages: | 1236-1240 |
| Country: | Chile |
| Language: | Español |
| Document type: | Artículo |
| Approach: | Caso clínico |
| English abstract | Digestive tract primary melanoma is uncommon. However, metastatic lesions are more frequent and occur mainly in the small intestine. We report a 69-year-old male patient who consulted for a hyperpigmented skin lesion on the left thigh associated with multiple subcutaneous nodules. The biopsy was compatible with melanoma and PET/CT was positive for metastases in nodules and in an inguinal lymph node. Radiotherapy and chemotherapy with pembrolizumab were performed with good response, associated with posterior resection of the inguinal lymph node and melanocytic lesions. At three years of follow-up, a new hypermetabolic focus in the proximal jejunum was found in a control PET/CT. An endoscopic biopsy confirmed that it was a recurrence of the melanoma. Laparoscopic resection with primary anastomosis was performed with good clinical evolution. The definitive biopsy showed a melanoma metastasis with two of three lymph nodes positive for metastasis and a non-mutated BRAF gene. In conclusion, a single intestinal recurrence of melanoma is rare and requires an active search, since it can be resected using minimally invasive techniques |
| Disciplines: | Medicina |
| Keyword: | Dermatología, Oncología, Melanoma cutáneo, Metástasis, Recidivas, Neoplasia intestinal |
| Keyword: | Dermatology, Oncology, Cutaneous melanoma, Metastasis, Relapse, Intestinal neoplasm |
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