| Journal: | Jornal brasileiro de pneumologia |
| Database: | PERIÓDICA |
| System number: | 000297387 |
| ISSN: | 1806-3713 |
| Authors: | Vitorio, Patricia K1 Coletta, Ester M2 Morrone, Nelson Lima, Carlos H Costa, Guilherme J Inoue, Daniel Hernandes, Fabiam B |
| Institutions: | 1Hospital do Servidor Publico Estadual, Servico de Doencas do Aparelho Respiratorio, Sao Paulo. Brasil 2Hospital do Servidor Publico Estadual, Servico de Anatomia Patologica, Sao Paulo. Brasil |
| Year: | 2004 |
| Season: | Ene-Feb |
| Volumen: | 30 |
| Number: | 1 |
| Pages: | 60-65 |
| Country: | Brasil |
| Language: | Portugués |
| Document type: | Artículo |
| Approach: | Caso clínico, descriptivo |
| English abstract | Epithelioid hemangioendothelioma (EHE), a very uncommon pleural tumor, was diagnosed in a 61-year-old man with work-related exposure to asbestos. Serohemorrhagic pleural effusion was diagnosed in the work-up of this patient, whose complaints were chest pain and weight loss. A lymphocytic predominance was present in the effusion, but no malignant cells were seen; pleural needle biopsy disclosed only a non-specific inflammatory process. Video thoracoscopy revealed nodules in parietal and visceral pleurae. A biopsy revealed a mesenchymal neoplasm; vascular markers CD 31, CD 34 and VIII factor were present; therefore, diagnosis of HE was accepted. The tumor was not responsive to cisplatin or etoposide and the patient died 3 months after the diagnosis |
| Portuguese abstract | Relata-se o caso de um paciente exposto profissionalmente a asbesto por dez anos e portador de um tumor pleural muito raro, o hemangioendotelioma epitelióde. O paciente apresentava derrame pleural serohemorrágico, sem evidência de células neoplásicas e com predomínio de linfócitos. A biópsia pleural por agulha revelou processo inflamatório crônico inespecífico, com áreas de tecido mixóide. A videotoracoscopia mostrou nódulos difusos nas pleuras parietal e visceral. A biópsia revelou neoplasia mesenquimal e eram semelhantes às áreas focais observadas na primeira biópsia. O estudo imunohistoquímico demonstrou a presença dos marcadores vasculares CD31, CD34 e Fator VIII, caracterizando a origem vascular do tumor. O paciente foi tratado com cisplatina e ectoposide, tendo o óbito ocorrido três meses após o diagnóstico |
| Disciplines: | Medicina |
| Keyword: | Diagnóstico, Neumología, Mesotelioma, Hemangioendotelioma, Pleura, Derrame pleural, Neoplasias, Asbesto |
| Keyword: | Medicine, Diagnosis, Pneumology, Mesothelioma, Hemangioendothelioma, Pleura, Pleural effusion, Neoplasms, Asbestos |
| Full text: | Texto completo (Ver HTML) |
