| Journal: | International braz j urol |
| Database: | PERIÓDICA |
| System number: | 000296703 |
| ISSN: | 1677-5538 |
| Authors: | Rocha, Marcos F1 Patrick, Tauzin-Fin Vasconcelos, Paulo L Ballanger, Philippe |
| Institutions: | 1University Hospital Pellegrin, Department of Urology, Bordeaux, Gironde. Francia |
| Year: | 2005 |
| Season: | Jul-Ago |
| Volumen: | 31 |
| Number: | 4 |
| Pages: | 299-308 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Caso clínico, analítico |
| English abstract | INTRODUCTION: We analyzed the changes in serum catecholamine concentrations, i.e. adrenaline and noradrenaline, in response to surgical stress in patients with pheochromocytoma who undergone videolaparoscopic adrenalectomy. MATERIALS AND METHODS: Between January 1998 and March 2002, 11 patients underwent 12 videolaparoscopic adrenalectomies. In one case, the adrenalectomy was bilateral. Serum catecholamines were measured at 6 surgical times: T0: control before induction; T1: following the induction, laryngoscopy and intubation sequence; T2: after installing the pneumoperitoneum; T3: during manipulation-exeresis of the pheochromocytoma; T4: following ablation of the pheochromocytoma; T5: in the recovery room following intervention when the patient was extubated and was hemodynamically stable. RESULTS: Mean concentrations of serum noradrenaline were significantly different when the T0 and T2 surgical times were compared (T0: 3161 pg/mL; T2: 40440 pg/mL; p < 0.01), T0 and T3 (T0: 3161 pg/mL; T3: 46021 pg/mL; p < 0.001), T1 and T3 (T1: 5531 pg/mL; T3: 46021 pg/mL; p < 0.01), T2 and T4 (T2: 40440 pg/mL; T4: 10773 pg/mL; p < 0.01) and T3 and T5 (T3: 46021 pg/mL; T5: 2549 pg/mL; p < 0.001). Mean concentrations of serum adrenaline were significantly different when the T0 and T3 surgical times were compared (T0: 738 pg/mL; T3: 27561 pg/mL; p < 0.01). CONCLUSION: The pneumoperitoneum significantly increases serum noradrenaline concentrations, manipulation of the adrenal gland significantly increases the serum concentrations |
| Disciplines: | Medicina |
| Keyword: | Cirugía, Sistema cardiovascular, Feocromocitoma, Catecolaminas, Laparoscopia, Glándulas adrenales |
| Keyword: | Medicine, Cardiovascular system, Surgery, Pheochromocytoma, Catecholamines, Laparoscopy, Adrenal glands |
| Full text: | Texto completo (Ver HTML) |
