Bonferroni's method to compare survival curves with recurrent events



Document title: Bonferroni's method to compare survival curves with recurrent events
Journal: Ingeniería industrial : actualidad y nuevas tendencias
Database: PERIÓDICA
System number: 000374504
ISSN: 1856-8327
Authors: 1
Institutions: 1Universidad de Carabobo, Facultad de Ingeniería, Valencia, Carabobo. Venezuela
Year:
Volumen: 3
Number: 10
Pages: 105-114
Country: Venezuela
Language: Español
Document type: Artículo
Approach: Experimental, aplicado
Spanish abstract Survival analysis provides useful statistical tools to study the occurrence of events such as epileptic seizures, viral diseases, malignant tumors, re-hospitalization of patients among others. This paper offers statistical tests of interest to epidemiologists, biostatisticians and other researchers interested in new methodologies to be applied in medicine and other related health research areas. The main objective is to propose a new procedure based on Bonferroni’s method to compare survival curves of population groups with recurrent events. Nonparametric comparison tests with recurrent events data are illustrated. The idea is applying this methodology with a sequential procedure controlling the error type I on multiple contrast tests. The hypothesis test is: H0: S1(z) = S2(z) = … = Sk(z), H1: At least one Sr(z) is different with r = 1, 2, ..., k. Where, Sr(z) is the survival curve of the rth group and its estimation is calculated by the Generalized Product Limit Estimator (GPLE or Kaplan-Meier estimator). The survival functions are estimated using R-language programs and counting processes
English abstract Survival analysis provides useful statistical tools to study the occurrence of events such as epileptic seizures, viral diseases, malignant tumors, re-hospitalization of patients among others. This paper offers statistical tests of interest to epidemiologists, biostatisticians and other researchers interested in new methodologies to be applied in medicine and other related health research areas. The main objective is to propose a new procedure based on Bonferroni’s method to compare survival curves of population groups with recurrent events. Nonparametric comparison tests with recurrent events data are illustrated. The idea is applying this methodology with a sequential procedure controlling the error type I on multiple contrast tests. The hypothesis test is: H0: S1(z) = S2(z) = … = Sk(z), H1: At least one Sr(z) is different with r = 1, 2, ..., k. Where, Sr(z) is the survival curve of the rth group and its estimation is calculated by the Generalized Product Limit Estimator (GPLE or Kaplan-Meier estimator). The survival functions are estimated using R-language programs and counting processes
Disciplines: Medicina,
Matemáticas
Keyword: Salud pública,
Estadísticas de salud,
Epidemiología,
Análisis de supervivencia,
Eventos recurrentes,
Pruebas estadísticas
Keyword: Medicine,
Mathematics,
Public health,
Health statistics,
Epidemiology,
Survival analysis,
Recurrent events,
Statistical tests
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