New insights into Canis familiaris papillomaviruses genetics and biology: Is the genetic characterization of CPV types and their variants an important clinical issue?



Document title: New insights into Canis familiaris papillomaviruses genetics and biology: Is the genetic characterization of CPV types and their variants an important clinical issue?
Journal: Genetics and molecular biology
Database: PERIÓDICA
System number: 000459280
ISSN: 1415-4757
Authors: 1
1
Institutions: 1Universidade Federal de Sergipe, Centro de Ciencias Biologicas e da Saude, Sao Cristovao, Sergipe. Brasil
Year:
Volumen: 45
Number: 3
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Descriptivo
English abstract Canis familiaris papillomavirus (CPV) is a member of the Papillomaviridae family and is found in dogs. After infection, the host can remain asymtomatic or develop benign ephitelial neoplasms such as papillomas and pigmented viral plaques, which can progress to cancer, in the form of squamous cell carcinoma (SCC). In humans, 227 types of human papillomavirus (HPV) have been described, with a well-established risk classification for cancer development. In addition, it is also known that variants of some high-risk HPV types may present different risks in respect of SCC development. In dogs, however, only a few types of CPV have been identified, despite the growing interest in this area, and knowledge on the genetic characterization of CPV variants is still scarce. Recent studies of CPV have shown that, as with HPV, benign neoplasia can develop into cancer, but it is believed that there are many more types and variants still to be described. Therefore, the aim of this study was to describe the genetics and biology of CPV, with the focus on what is known about lesions, geographic localization, virus types and variants
Disciplines: Biología,
Medicina veterinaria y zootecnia
Keyword: Genética,
Virus,
Pequeñas especies,
Papiloma,
Canis familiaris,
Perros,
Revisión bibliográfica
Keyword: Genetics,
Virus,
Companion animals,
Dogs,
Papilloma,
Bibliographic review
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