| Journal: | Brazilian journal of chemical engineering |
| Database: | PERIÓDICA |
| System number: | 000308948 |
| ISSN: | 0104-6632 |
| Authors: | Silva, O.S1 Rocha, S.C.S Marsal, S.C |
| Institutions: | 1Universidade Estadual de Campinas, Faculdade de Engenharia Quimica, Campinas, Sao Paulo. Brasil |
| Year: | 2004 |
| Season: | Jun |
| Volumen: | 21 |
| Number: | 2 |
| Pages: | 325-333 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Experimental, aplicado |
| English abstract | The objective of this work was to study the coating of microcrystalline cellulose with a polymeric suspension in a fluidized bed. The coating operation was carried out using a fluidized bed with top spraying by a double-fluid nozzle. The fluidized bed consists of a cylindrical column made of plexiglass with a height of 0.6 m and an inner diameter of 0.14 m. The polymeric coating suspension was formulated using Eudragit® as the basic component. As the quality of the coating product is greatly affected by the spraying characteristics, the influence of the flow rate of the coating suspension and the moisture content of the particles on the agglomeration index and efficiency of the process of coating microcrystalline cellulose was analyzed |
| Disciplines: | Química |
| Keyword: | Química farmacéutica, Ingeniería química, Celulosa microcristalina, Contenido de humedad, Recubrimiento, Fluidización |
| Keyword: | Chemistry, Medicinal chemistry, Chemical engineering, Microcrystalline cellulose, Moisture content, Coating, Fluidization |
| Full text: | Texto completo (Ver HTML) |
