| Journal: | Brazilian journal of chemical engineering |
| Database: | PERIÓDICA |
| System number: | 000309006 |
| ISSN: | 0104-6632 |
| Authors: | Castro, B.D1 Aznar, M |
| Institutions: | 1Universidade Estadual de Campinas, Faculdade de Engenharia Quimica, Campinas, Sao Paulo. Brasil |
| Year: | 2005 |
| Season: | Sep |
| Volumen: | 22 |
| Number: | 3 |
| Pages: | 463-470 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Experimental, aplicado |
| English abstract | Liquid-liquid extraction using aqueous two-phase systems is a highly efficient technique for separation and purification of biomolecules due to the mild properties of both liquid phases. Reliable data on the phase behavior of these systems are essential for the design and operation of new separation processes; several authors reported phase diagrams for polymer-polymer systems, but data on polymer-salt systems are still relatively scarce. In this work, experimental liquid-liquid equilibrium data on water + polyethylene glycol 8000 + magnesium sulfate and water + polyethylene glycol 8000 + sodium sulfate aqueous two-phase systems were obtained at 35°C. Both equilibrium phases were analyzed by lyophilization and ashing. Experimental results were correlated with a mass-fraction-based NRTL activity coefficient model. New interaction parameters were estimated with the Simplex method. The mean deviations between the experimental and calculated compositions in both equilibrium phases is about 2% |
| Disciplines: | Química |
| Keyword: | Ingeniería química, Equilibrio líquido-líquido, Sistema acuoso bifásico, Polietilenglicol, Modelos termodinámicos |
| Keyword: | Chemistry, Chemical engineering, Liquid-liquid equilibrium, Aqueous two-phase system, Poly(ethylene glycol), Thermodynamic models |
| Full text: | Texto completo (Ver HTML) |
