| Journal: | Brazilian journal of chemical engineering |
| Database: | PERIÓDICA |
| System number: | 000309100 |
| ISSN: | 0104-6632 |
| Authors: | Rodrigues, M.A1 Li, Jun2 Almeida, A.J3 Matos, H.A Azevedo, E. Gomes de |
| Institutions: | 1Instituto Superior Tecnico, Departamento de Engenharia Quimica, Lisboa. Portugal 2Xiamen University, Department of Chemical Engineering, Xiamen, Fujian. China 3Universidade de Lisboa, Faculdade de Farmacia, Lisboa. Portugal |
| Year: | 2006 |
| Season: | Jun |
| Volumen: | 23 |
| Number: | 2 |
| Pages: | 205-212 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Experimental, aplicado |
| English abstract | Techniques involving supercritical carbon dioxide have been successfully used for the formation of drug particles with controlled size distributions. However, these processes show some limitations, particularly in processing aqueous solutions. A diagram walking algorithm based on available experimental data was developed to evaluate the effect of ethanol on the efficiency of water removal processes under different process conditions. Ethanol feeding was the key parameter resulting in a tenfold increase in the efficiency of water extraction |
| Disciplines: | Química |
| Keyword: | Química farmacéutica, Soluciones acuosas, Remoción de agua, Dióxido de carbono supercrítico |
| Keyword: | Chemistry, Medicinal chemistry, Aqueous solutions, Water removal, Supercritical carbon dioxide |
| Full text: | Texto completo (Ver HTML) |
