Healing effect of the ointment made of Equisetum pyramidale in the treatment of cutaneous lesions in diabetic rats



Document title: Healing effect of the ointment made of Equisetum pyramidale in the treatment of cutaneous lesions in diabetic rats
Journal: Brazilian archives of biology and technology
Database: PERIÓDICA
System number: 000362754
ISSN: 1516-8913
Authors: 1
2
2
3
1
3
Institutions: 1Universidade Federal de Mato Grosso do Sul, Programa de Pos-Graduacao em Saude e Desenvolvimento da Regiao Centro-Oeste, Campo Grande, Mato Grosso do Sul. Brasil
2Universidade Federal de Mato Grosso do Sul, Programa de Pos-graduacao em Doencas Infecciosas e Parasitarias, Campo Grande, Mato Grosso do Sul. Brasil
3Universidade Estadual de Maringa, Maringa, Parana. Brasil
Year:
Season: May-Jun
Volumen: 56
Number: 3
Pages: 377-382
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Experimental, aplicado
English abstract This study aimed to evaluate the anti-inflammatory and repair effects of the ethanolic extract and ointment of Equisetum pyramidale on the skin lesions of rats induced to diabetes. After the induction of diabetes with alloxan, a surgical procedure was performed on the back of each rat. Then, they were separated into treatment groups: G1 ethanol extract of E. pyramidale; G2-ointment (extract of E. pyramidale 80g + 20g of vaseline:lanolin 1:1); G3 control (vehicle vaseline:lanolin 1:1); and G4-no treatment during 3, 7 and 14 days. The samples were embedded in paraffin and stained with hematoxylin-eosin for histological analysis. The findings showed that the use of ethanolic extract as well as the ointment decreased the inflammatory cells at the site of inflammation, resulting a faster healing, with less crusting and lower amount of secretion in comparison to the control group. Therapy with topical herbal was an effective method in the inflammatory process of tissue repair, contributing to a faster and more organized tissue re-epithelialization
Disciplines: Medicina
Keyword: Farmacología,
Medicina experimental,
Diabetes,
Cicatrización,
Lesiones cutáneas,
Plantas medicinales,
Actividad antiinflamatoria,
Equisetum pyramidale
Keyword: Medicine,
Experimental medicine,
Pharmacology,
Diabetes,
Wound healing,
Skin lesions,
Medicinal plants,
Antiinflammatory activity,
Equisetum pyramidale
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