Revista: | Brazilian archives of biology and technology |
Base de datos: | PERIÓDICA |
Número de sistema: | 000362754 |
ISSN: | 1516-8913 |
Autores: | Correa, Andreia Cristina Lopes1 Hans-Filho, Guinter2 Dourado, Doroty Mesquita2 Matias, Rosemary3 Silva, Iandara Schettert da1 Sarragiotto, Maria Helena3 |
Instituciones: | 1Universidade Federal de Mato Grosso do Sul, Programa de Pos-Graduacao em Saude e Desenvolvimento da Regiao Centro-Oeste, Campo Grande, Mato Grosso do Sul. Brasil 2Universidade Federal de Mato Grosso do Sul, Programa de Pos-graduacao em Doencas Infecciosas e Parasitarias, Campo Grande, Mato Grosso do Sul. Brasil 3Universidade Estadual de Maringa, Maringa, Parana. Brasil |
Año: | 2013 |
Periodo: | May-Jun |
Volumen: | 56 |
Número: | 3 |
Paginación: | 377-382 |
País: | Brasil |
Idioma: | Inglés |
Tipo de documento: | Artículo |
Enfoque: | Experimental, aplicado |
Resumen en inglés | This study aimed to evaluate the anti-inflammatory and repair effects of the ethanolic extract and ointment of Equisetum pyramidale on the skin lesions of rats induced to diabetes. After the induction of diabetes with alloxan, a surgical procedure was performed on the back of each rat. Then, they were separated into treatment groups: G1 ethanol extract of E. pyramidale; G2-ointment (extract of E. pyramidale 80g + 20g of vaseline:lanolin 1:1); G3 control (vehicle vaseline:lanolin 1:1); and G4-no treatment during 3, 7 and 14 days. The samples were embedded in paraffin and stained with hematoxylin-eosin for histological analysis. The findings showed that the use of ethanolic extract as well as the ointment decreased the inflammatory cells at the site of inflammation, resulting a faster healing, with less crusting and lower amount of secretion in comparison to the control group. Therapy with topical herbal was an effective method in the inflammatory process of tissue repair, contributing to a faster and more organized tissue re-epithelialization |
Disciplinas: | Medicina |
Palabras clave: | Farmacología, Medicina experimental, Diabetes, Cicatrización, Lesiones cutáneas, Plantas medicinales, Actividad antiinflamatoria, Equisetum pyramidale |
Keyword: | Medicine, Experimental medicine, Pharmacology, Diabetes, Wound healing, Skin lesions, Medicinal plants, Antiinflammatory activity, Equisetum pyramidale |
Texto completo: | Texto completo (Ver HTML) |